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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS3
All Species:
23.94
Human Site:
S104
Identified Species:
65.83
UniProt:
Q99687
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99687
NP_001009813.1
375
41115
S104
G
D
V
C
S
S
D
S
F
N
E
D
I
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541536
393
42963
S116
G
D
V
C
S
S
D
S
F
N
E
D
I
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P97368
378
41738
S107
G
D
V
C
S
S
D
S
F
N
E
D
I
A
A
Rat
Rattus norvegicus
NP_001101942
378
41597
S107
G
D
V
C
S
S
D
S
F
N
E
D
I
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZY13
451
48950
S110
G
D
V
C
S
S
D
S
F
N
E
D
I
A
V
Zebra Danio
Brachydanio rerio
NP_571853
415
45613
S119
S
E
K
P
I
F
S
S
N
P
E
L
D
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
S135
G
D
V
C
S
S
E
S
F
N
E
D
I
A
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
D144
C
S
S
A
S
F
K
D
D
L
N
E
F
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
S56
R
T
N
I
A
V
G
S
P
V
N
P
V
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
86
N.A.
89.4
90.4
N.A.
N.A.
N.A.
63.1
61.6
N.A.
45.7
N.A.
32.6
N.A.
Protein Similarity:
100
N.A.
N.A.
88.5
N.A.
92.5
93.6
N.A.
N.A.
N.A.
71.1
70.8
N.A.
57.4
N.A.
45.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
13.3
N.A.
86.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
20
N.A.
93.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
0
0
0
0
0
0
0
67
45
% A
% Cys:
12
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
56
12
12
0
0
67
12
0
0
% D
% Glu:
0
12
0
0
0
0
12
0
0
0
78
12
0
0
0
% E
% Phe:
0
0
0
0
0
23
0
0
67
0
0
0
12
0
0
% F
% Gly:
67
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
0
0
0
0
0
0
67
0
0
% I
% Lys:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
12
0
0
0
0
0
12
67
23
0
0
12
0
% N
% Pro:
0
0
0
12
0
0
0
0
12
12
0
12
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
12
12
0
78
67
12
89
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
67
0
0
12
0
0
0
12
0
0
12
12
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _