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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEZ1
All Species:
25.15
Human Site:
S51
Identified Species:
69.17
UniProt:
Q99689
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99689
NP_005094.1
392
45119
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Chimpanzee
Pan troglodytes
XP_001145607
393
45328
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Rhesus Macaque
Macaca mulatta
XP_001110806
392
45130
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Dog
Lupus familis
XP_849234
392
45109
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0X8
392
45184
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Rat
Rattus norvegicus
P97577
393
45225
S51
S
E
L
E
N
F
S
S
E
I
I
S
F
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423333
393
43724
V51
F
K
S
M
E
D
L
V
Q
E
F
D
E
K
L
Frog
Xenopus laevis
NP_001085822
392
45514
E51
E
L
E
N
F
S
S
E
I
I
S
F
K
S
M
Zebra Danio
Brachydanio rerio
NP_998561
394
45101
S53
F
S
E
L
E
N
F
S
E
M
M
S
F
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
96.1
N.A.
94.6
95.9
N.A.
N.A.
63
77
70.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
99.7
97.4
N.A.
97.9
97.4
N.A.
N.A.
76
88
82.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% D
% Glu:
12
67
23
67
23
0
0
12
78
12
0
0
12
0
0
% E
% Phe:
23
0
0
0
12
67
12
0
0
0
12
12
78
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
78
67
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
12
89
0
% K
% Leu:
0
12
67
12
0
0
12
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
12
0
0
0
0
0
12
12
0
0
0
12
% M
% Asn:
0
0
0
12
67
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
12
12
0
0
12
78
78
0
0
12
78
0
12
78
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _