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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBBP8 All Species: 15.76
Human Site: S445 Identified Species: 31.52
UniProt: Q99708 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99708 NP_002885.1 897 101942 S445 K S L G G R T S K R K K T E E
Chimpanzee Pan troglodytes XP_001153277 895 101751 R445 L G G R T S K R K K T E E E S
Rhesus Macaque Macaca mulatta XP_001093018 893 101172 T445 L K S L G G R T S K R K K T E
Dog Lupus familis XP_537299 900 102210 S444 V P L K S L G S R T S K R R K
Cat Felis silvestris
Mouse Mus musculus NP_001074692 893 100813 S444 K S L G G K A S K R K R T E E
Rat Rattus norvegicus NP_001127889 893 100686 S444 K S L G G K A S K R K R T E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505639 582 63108 S148 G L G L Q E E S Q Q Q Q E E E
Chicken Gallus gallus XP_419158 912 103512 Q445 F L L A H Q K Q P E G R C A K
Frog Xenopus laevis NP_001085825 856 98274 Q416 S P N K S D A Q M G K Y I F D
Zebra Danio Brachydanio rerio NP_001012518 651 74336 A217 N G K G V L V A E T C E M D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002298444 629 71562 S195 Q D E V R K K S E K V A E K T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRT1 588 67213 L154 Q V K G L D E L S E D G I N M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 91.1 82.3 N.A. 76.3 75.3 N.A. 34.5 57.1 45.1 32.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 93.9 88 N.A. 84.1 84.1 N.A. 42.4 70.3 60.9 46.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 20 20 N.A. 80 80 N.A. 20 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 40 33.3 N.A. 93.3 93.3 N.A. 46.6 26.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 21 N.A. N.A. 21 N.A. N.A.
Protein Similarity: 37 N.A. N.A. 36.2 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 25 9 0 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % C
% Asp: 0 9 0 0 0 17 0 0 0 0 9 0 0 9 9 % D
% Glu: 0 0 9 0 0 9 17 0 17 17 0 17 25 42 42 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 17 17 42 34 9 9 0 0 9 9 9 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 25 9 17 17 0 25 25 0 34 25 34 25 9 9 17 % K
% Leu: 17 17 42 17 9 17 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 17 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 17 0 0 0 9 9 0 17 9 9 9 9 0 0 0 % Q
% Arg: 0 0 0 9 9 9 9 9 9 25 9 25 9 9 0 % R
% Ser: 9 25 9 0 17 9 0 50 17 0 9 0 0 0 9 % S
% Thr: 0 0 0 0 9 0 9 9 0 17 9 0 25 9 17 % T
% Val: 9 9 0 9 9 0 9 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _