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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT5
All Species:
28.48
Human Site:
S241
Identified Species:
62.67
UniProt:
Q99719
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99719
NP_002679.2
369
42777
S241
Q
D
R
E
L
K
E
S
A
P
F
A
V
I
G
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
R240
L
V
K
K
I
K
D
R
L
P
L
A
V
V
G
Rhesus Macaque
Macaca mulatta
XP_001105256
378
43827
S250
Q
D
R
E
L
K
E
S
A
P
F
A
V
I
G
Dog
Lupus familis
XP_543545
378
43755
S250
Q
D
R
E
L
K
E
S
A
P
F
A
V
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2Q6
369
42729
S241
Q
D
R
E
L
K
E
S
A
P
F
A
V
I
G
Rat
Rattus norvegicus
Q9JJM9
369
42834
S241
Q
D
R
E
L
K
E
S
A
P
F
A
V
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509185
527
59238
S390
Q
D
Q
A
L
K
D
S
I
P
F
A
V
I
G
Chicken
Gallus gallus
Q5ZMH1
349
40206
S233
Q
T
R
V
L
K
A
S
I
P
F
A
V
I
G
Frog
Xenopus laevis
Q63ZQ1
352
40432
S233
Q
T
R
L
L
K
A
S
I
P
F
T
V
V
G
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
K260
F
D
E
D
M
E
D
K
S
D
N
D
K
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
A232
Q
V
K
Q
L
K
E
A
V
P
F
A
V
C
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
94.1
93.3
N.A.
98.9
98.3
N.A.
51
57.9
57.4
42.5
N.A.
58.2
N.A.
N.A.
N.A.
Protein Similarity:
100
63.3
95.5
95.2
N.A.
100
99.7
N.A.
60.1
72.9
73.4
63.4
N.A.
75.3
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
100
N.A.
100
100
N.A.
73.3
73.3
60
13.3
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
86.6
73.3
66.6
46.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
19
10
46
0
0
82
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
64
0
10
0
0
28
0
0
10
0
10
0
0
0
% D
% Glu:
0
0
10
46
0
10
55
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
91
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
28
0
0
0
0
73
0
% I
% Lys:
0
0
19
10
0
91
0
10
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
10
82
0
0
0
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% P
% Gln:
82
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
64
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
73
10
0
0
0
0
0
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
19
0
10
0
0
0
0
10
0
0
0
91
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _