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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGMAR1
All Species:
36.67
Human Site:
S143
Identified Species:
73.33
UniProt:
Q99720
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99720
NP_005857.1
223
25128
S143
W
R
E
G
T
T
K
S
E
V
F
Y
P
G
E
Chimpanzee
Pan troglodytes
XP_001163744
215
24311
S135
W
R
E
G
T
T
K
S
E
V
F
Y
P
G
E
Rhesus Macaque
Macaca mulatta
XP_001095863
203
22785
S123
W
R
E
G
T
T
K
S
E
V
F
Y
P
G
E
Dog
Lupus familis
XP_852544
223
25083
S143
W
R
E
G
T
T
K
S
E
V
F
Y
P
G
E
Cat
Felis silvestris
Mouse
Mus musculus
O55242
223
25231
S143
W
K
E
G
T
T
K
S
E
V
F
Y
P
G
E
Rat
Rattus norvegicus
Q9R0C9
223
25251
S143
W
R
E
G
T
T
K
S
E
V
Y
Y
P
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL84
222
24584
S142
W
K
E
G
T
T
R
S
E
I
Y
Y
P
G
D
Frog
Xenopus laevis
Q6DCU6
221
24677
S140
W
K
E
G
T
T
K
S
E
I
F
Y
P
G
D
Zebra Danio
Brachydanio rerio
Q7ZWG9
222
24922
S141
W
K
E
G
T
T
K
S
E
T
Y
Y
P
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783805
210
23776
R110
D
T
S
G
H
S
G
R
Y
W
A
N
V
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32352
222
24877
V121
G
T
E
G
H
T
G
V
H
F
A
D
D
Y
F
Red Bread Mold
Neurospora crassa
Q92254
256
28227
Y162
G
R
H
T
A
D
D
Y
F
H
I
L
T
G
T
Conservation
Percent
Protein Identity:
100
94.1
91
97.7
N.A.
90.1
93.7
N.A.
N.A.
65.9
67.7
63.6
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
95
91
98.6
N.A.
93.7
95.9
N.A.
N.A.
79.3
84.7
79.3
N.A.
N.A.
N.A.
N.A.
69.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
66.6
80
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
46.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
9
0
0
0
0
9
9
0
34
% D
% Glu:
0
0
84
0
0
0
0
0
75
0
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
50
0
0
0
9
% F
% Gly:
17
0
0
92
0
0
17
0
0
0
0
0
0
84
0
% G
% His:
0
0
9
0
17
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
9
0
0
0
0
% I
% Lys:
0
34
0
0
0
0
67
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
0
0
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
9
0
75
0
0
0
0
0
9
0
% S
% Thr:
0
17
0
9
75
84
0
0
0
9
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
9
0
50
0
0
9
0
0
% V
% Trp:
75
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
9
0
25
75
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _