KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGMAR1
All Species:
35.15
Human Site:
T132
Identified Species:
70.3
UniProt:
Q99720
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99720
NP_005857.1
223
25128
T132
S
D
T
I
I
S
G
T
F
H
Q
W
R
E
G
Chimpanzee
Pan troglodytes
XP_001163744
215
24311
T124
S
D
T
I
I
S
G
T
F
H
Q
W
R
E
G
Rhesus Macaque
Macaca mulatta
XP_001095863
203
22785
T112
S
D
T
I
I
S
G
T
F
H
Q
W
R
E
G
Dog
Lupus familis
XP_852544
223
25083
T132
S
D
T
I
I
S
G
T
F
H
Q
W
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
O55242
223
25231
T132
S
D
T
I
I
S
G
T
F
H
Q
W
K
E
G
Rat
Rattus norvegicus
Q9R0C9
223
25251
T132
S
D
T
I
I
S
G
T
F
H
Q
W
R
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL84
222
24584
T131
Y
D
T
I
I
S
G
T
F
R
Q
W
K
E
G
Frog
Xenopus laevis
Q6DCU6
221
24677
T129
S
D
T
I
L
S
G
T
F
R
Q
W
K
E
G
Zebra Danio
Brachydanio rerio
Q7ZWG9
222
24922
T130
S
D
T
I
I
S
G
T
F
R
Q
W
K
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783805
210
23776
G99
T
E
Y
I
L
F
F
G
T
A
V
D
T
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32352
222
24877
G110
S
E
Y
L
I
L
F
G
T
A
V
G
T
E
G
Red Bread Mold
Neurospora crassa
Q92254
256
28227
E151
F
G
T
A
I
G
T
E
G
H
T
G
R
H
T
Conservation
Percent
Protein Identity:
100
94.1
91
97.7
N.A.
90.1
93.7
N.A.
N.A.
65.9
67.7
63.6
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
95
91
98.6
N.A.
93.7
95.9
N.A.
N.A.
79.3
84.7
79.3
N.A.
N.A.
N.A.
N.A.
69.9
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
80
80
86.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
30.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
46.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
17
0
0
0
0
0
9
0
0
0
0
0
84
0
% E
% Phe:
9
0
0
0
0
9
17
0
75
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
75
17
9
0
0
17
0
0
92
% G
% His:
0
0
0
0
0
0
0
0
0
59
0
0
0
9
0
% H
% Ile:
0
0
0
84
84
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% K
% Leu:
0
0
0
9
17
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
25
0
0
50
0
0
% R
% Ser:
75
0
0
0
0
75
0
0
0
0
0
0
0
9
0
% S
% Thr:
9
0
84
0
0
0
9
75
17
0
9
0
17
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% W
% Tyr:
9
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _