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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BARD1
All Species:
25.15
Human Site:
Y446
Identified Species:
55.33
UniProt:
Q99728
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99728
NP_000456.2
777
86648
Y446
G
D
I
P
S
V
E
Y
L
L
Q
N
G
S
D
Chimpanzee
Pan troglodytes
XP_526019
777
86498
Y446
G
D
I
P
S
V
E
Y
L
L
Q
N
G
S
D
Rhesus Macaque
Macaca mulatta
XP_001084740
777
86841
Y446
G
D
I
P
S
V
E
Y
L
L
Q
N
G
S
D
Dog
Lupus familis
XP_852715
923
103188
Y592
G
D
V
P
S
V
E
Y
L
L
Q
N
G
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O70445
765
84236
Y434
G
D
I
P
S
V
E
Y
L
L
Q
N
G
N
D
Rat
Rattus norvegicus
Q9QZH2
768
84530
Y436
G
D
I
S
S
V
E
Y
L
L
Q
N
G
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519813
231
26178
Chicken
Gallus gallus
NP_001026417
750
82934
K432
N
G
A
D
P
N
V
K
D
N
A
G
W
T
P
Frog
Xenopus laevis
NP_001082131
772
86896
D438
G
D
I
Q
G
V
E
D
L
L
N
S
G
A
N
Zebra Danio
Brachydanio rerio
XP_001921099
334
36093
Q39
G
V
V
E
E
L
L
Q
Q
G
A
L
L
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188296
940
102732
S511
G
D
E
N
E
V
K
S
L
L
V
Q
G
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.3
68.3
N.A.
69.5
68.5
N.A.
22.5
51.6
47.3
22.1
N.A.
N.A.
N.A.
N.A.
26.8
Protein Similarity:
100
99.7
97.5
74.4
N.A.
81
80.9
N.A.
26.7
67.9
62.8
31.6
N.A.
N.A.
N.A.
N.A.
41.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
0
53.3
6.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
6.6
73.3
26.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
19
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
73
0
10
0
0
0
10
10
0
0
0
0
0
64
% D
% Glu:
0
0
10
10
19
0
64
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
82
10
0
0
10
0
0
0
0
10
0
10
73
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
73
73
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
10
10
55
0
28
10
% N
% Pro:
0
0
0
46
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
10
10
0
55
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
55
0
0
10
0
0
0
10
0
37
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% T
% Val:
0
10
19
0
0
73
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _