Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BARD1 All Species: 5.45
Human Site: Y597 Identified Species: 12
UniProt: Q99728 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99728 NP_000456.2 777 86648 Y597 V I L K A K K Y T E F D S T V
Chimpanzee Pan troglodytes XP_526019 777 86498 Y597 A I L K A K K Y T E F D S T V
Rhesus Macaque Macaca mulatta XP_001084740 777 86841 C597 A I L K A K K C T E F D S T V
Dog Lupus familis XP_852715 923 103188 C743 A I L K A K K C A E F D N T V
Cat Felis silvestris
Mouse Mus musculus O70445 765 84236 C585 T V L K A K K C M E F D S T V
Rat Rattus norvegicus Q9QZH2 768 84530 C588 T V L K A K K C A E F D N T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519813 231 26178 I72 G D T V Q R T I K C M L G I L
Chicken Gallus gallus NP_001026417 750 82934 C571 T V L K A R R C T E F N S T V
Frog Xenopus laevis NP_001082131 772 86896 C593 K M L K A S I C A E Y D S T V
Zebra Danio Brachydanio rerio XP_001921099 334 36093 T175 P I M P S T L T T L H G V L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188296 940 102732 R662 C S D L L Q G R V V D E F S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.3 68.3 N.A. 69.5 68.5 N.A. 22.5 51.6 47.3 22.1 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.7 97.5 74.4 N.A. 81 80.9 N.A. 26.7 67.9 62.8 31.6 N.A. N.A. N.A. N.A. 41.4
P-Site Identity: 100 93.3 86.6 73.3 N.A. 73.3 66.6 N.A. 0 60 53.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 86.6 80 N.A. 80 80 N.A. 13.3 86.6 66.6 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 0 0 73 0 0 0 28 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 55 0 10 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 0 0 10 64 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 73 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 64 0 10 0 0 % F
% Gly: 10 0 0 0 0 0 10 0 0 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 46 0 0 0 0 10 10 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 73 0 55 55 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 73 10 10 0 10 0 0 10 0 10 0 10 10 % L
% Met: 0 10 10 0 0 0 0 0 10 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 19 0 10 % N
% Pro: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 10 10 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 10 10 0 0 0 0 0 0 55 10 0 % S
% Thr: 28 0 10 0 0 10 10 10 46 0 0 0 0 73 0 % T
% Val: 10 28 0 10 0 0 0 0 10 10 0 0 10 0 73 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _