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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LITAF All Species: 23.94
Human Site: S22 Identified Species: 52.67
UniProt: Q99732 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99732 NP_001129944.1 161 17107 S22 S A P S A P P S Y E E T V A V
Chimpanzee Pan troglodytes XP_001142957 161 17074 S22 S A P S A P P S Y E E T V A V
Rhesus Macaque Macaca mulatta XP_001105141 161 16988 S22 A A P S A P P S Y E E T V A V
Dog Lupus familis XP_547124 161 16940 S22 S V P T A P P S Y E E T V A V
Cat Felis silvestris
Mouse Mus musculus Q9JLJ0 161 16927 T22 V V P T A P P T Y E E T V G V
Rat Rattus norvegicus P0C0T0 161 17011 T22 V M P T A P P T Y E E T V G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509852 154 16188 T22 A P P S Y E E T L A F S S C Y
Chicken Gallus gallus Q8QGW7 148 15994 G21 P S Y E E T V G I N V N Y P H
Frog Xenopus laevis Q8AVW3 207 22088 P67 P N P G F Y P P P G P Y V P M
Zebra Danio Brachydanio rerio Q6GMG8 163 17432 S24 V G H P P P P S Y D E I S G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191550 219 23170 P80 A A G Y P M Q P P P G A G Y P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.2 88.8 N.A. 85.7 86.9 N.A. 74.5 64.5 32.3 38.6 N.A. N.A. N.A. N.A. 33.7
Protein Similarity: 100 100 99.3 93.1 N.A. 92.5 91.9 N.A. 82.6 75.1 43.4 53.9 N.A. N.A. N.A. N.A. 43.8
P-Site Identity: 100 100 93.3 86.6 N.A. 66.6 66.6 N.A. 13.3 0 20 33.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 33.3 6.6 26.6 40 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 37 0 0 55 0 0 0 0 10 0 10 0 37 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 10 10 0 0 55 64 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 10 10 0 0 0 10 0 10 10 0 10 28 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % N
% Pro: 19 10 73 10 19 64 73 19 19 10 10 0 0 19 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 10 0 37 0 0 0 46 0 0 0 10 19 0 0 % S
% Thr: 0 0 0 28 0 10 0 28 0 0 0 55 0 0 0 % T
% Val: 28 19 0 0 0 0 10 0 0 0 10 0 64 0 55 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 10 10 0 0 64 0 0 10 10 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _