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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
21.21
Human Site:
S74
Identified Species:
35.9
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
S74
T
P
H
L
P
P
C
S
P
P
K
Q
G
K
K
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
S74
T
P
H
L
P
P
C
S
P
P
K
Q
G
K
K
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
S74
T
P
H
L
P
P
C
S
P
P
K
Q
G
K
K
Dog
Lupus familis
XP_537648
559
62507
P74
P
H
L
P
P
C
S
P
P
K
Q
G
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
S75
T
P
R
L
S
P
C
S
P
P
K
L
G
K
K
Rat
Rattus norvegicus
NP_001101768
561
62295
S75
T
P
H
L
S
P
C
S
P
P
K
L
G
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
S74
I
P
P
T
L
S
C
S
P
P
K
Q
S
R
K
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
S94
L
P
A
S
M
L
G
S
P
P
K
Q
R
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
D169
L
L
D
R
L
S
I
D
E
R
Q
E
E
E
V
Honey Bee
Apis mellifera
XP_625142
549
62089
Q83
H
D
N
T
I
S
T
Q
T
P
Q
C
V
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
V77
V
A
A
K
E
S
P
V
G
S
I
R
S
P
S
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
P66
V
D
S
S
P
N
T
P
T
N
G
I
E
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
A77
N
L
N
S
S
D
G
A
L
P
A
R
T
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
100
20
N.A.
80
80
N.A.
0
N.A.
53.3
40
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
80
86.6
N.A.
0
N.A.
60
40
N.A.
20
33.3
N.A.
6.6
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
0
0
8
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
43
0
0
0
0
8
0
8
0
% C
% Asp:
0
15
8
0
0
8
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
8
15
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
15
0
8
0
8
8
36
0
0
% G
% His:
8
8
29
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
50
0
8
50
50
% K
% Leu:
15
15
8
36
15
8
0
0
8
0
0
15
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
15
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
50
8
8
36
36
8
15
58
65
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
22
36
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
8
0
15
8
15
0
% R
% Ser:
0
0
8
22
22
29
8
50
0
8
0
0
15
0
8
% S
% Thr:
36
0
0
15
0
0
15
0
15
0
0
0
8
0
0
% T
% Val:
15
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _