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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXN2
All Species:
36.06
Human Site:
T122
Identified Species:
61.03
UniProt:
Q99757
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99757
NP_036605.2
166
18383
T122
K
V
D
I
D
D
H
T
D
L
A
I
E
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106286
107
12110
D87
M
K
N
G
D
V
V
D
K
F
V
G
I
K
D
Dog
Lupus familis
XP_531748
250
26635
T206
K
V
D
I
D
D
H
T
D
L
A
L
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P97493
166
18237
T122
K
V
D
I
D
D
H
T
D
L
A
I
E
Y
E
Rat
Rattus norvegicus
P97615
166
18213
T122
K
V
D
I
D
D
H
T
D
L
A
I
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506137
512
55735
T467
K
V
D
I
D
D
N
T
D
L
A
I
E
Y
E
Chicken
Gallus gallus
NP_001026581
140
15152
T105
K
V
D
I
D
D
H
T
D
L
A
I
E
Y
E
Frog
Xenopus laevis
NP_001080066
170
18566
T125
K
V
D
I
D
D
H
T
D
L
A
L
E
F
E
Zebra Danio
Brachydanio rerio
NP_991204
166
18440
T121
K
V
D
I
D
E
H
T
D
L
A
I
E
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393603
136
15176
S92
K
V
D
I
D
E
N
S
D
L
A
L
D
Y
E
Nematode Worm
Caenorhab. elegans
Q17424
145
15683
G100
K
I
N
V
D
H
A
G
E
L
A
M
D
Y
G
Sea Urchin
Strong. purpuratus
XP_790171
172
18920
Q128
K
V
D
I
D
E
L
Q
D
L
A
I
G
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41864
167
18055
P121
K
V
N
T
D
D
S
P
N
V
A
S
T
Y
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22217
103
11216
E83
L
L
F
K
N
G
K
E
V
A
K
V
V
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
56
54.7
N.A.
88.5
87.9
N.A.
27.1
63.8
64.7
56.6
N.A.
N.A.
42.1
37.3
39.5
Protein Similarity:
100
N.A.
59.6
58.4
N.A.
93.3
92.1
N.A.
30
68
74.1
71.6
N.A.
N.A.
61.4
58.4
60.4
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
100
100
N.A.
93.3
100
86.6
86.6
N.A.
N.A.
66.6
33.3
60
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
N.A.
100
73.3
73.3
Percent
Protein Identity:
N.A.
29.3
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
49.1
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
60
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
86
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
72
0
93
58
0
8
72
0
0
0
15
0
8
% D
% Glu:
0
0
0
0
0
22
0
8
8
0
0
0
58
0
58
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
15
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
0
0
8
8
8
29
% G
% His:
0
0
0
0
0
8
50
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
72
0
0
0
0
0
0
0
50
8
0
0
% I
% Lys:
86
8
0
8
0
0
8
0
8
0
8
0
0
8
0
% K
% Leu:
8
8
0
0
0
0
8
0
0
79
0
22
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
22
0
8
0
15
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
58
0
0
0
0
8
0
0
% T
% Val:
0
79
0
8
0
8
8
0
8
8
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _