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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXN2 All Species: 9.39
Human Site: T28 Identified Species: 15.9
UniProt: Q99757 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99757 NP_036605.2 166 18383 T28 Q G Q W P P L T S R A L Q T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106286 107 12110 M22 L V N S E T P M V V D F H T Q
Dog Lupus familis XP_531748 250 26635 A112 K P P Q G R W A P L T C R A L
Cat Felis silvestris
Mouse Mus musculus P97493 166 18237 T28 Q G V W A S L T S K T L Q T P
Rat Rattus norvegicus P97615 166 18213 T28 Q G V W A S L T S T S L Q T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506137 512 55735 L365 S E R A G P L L A R A R P G P
Chicken Gallus gallus NP_001026581 140 15152 A34 S Q G L P G R A F G S S A I R
Frog Xenopus laevis NP_001080066 170 18566 G32 F S T L L S N G V R S H G L K
Zebra Danio Brachydanio rerio NP_991204 166 18440 S27 V L V L P S S S S S R S S F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393603 136 15176 Q26 A N A P A Q E Q A I S T T F K
Nematode Worm Caenorhab. elegans Q17424 145 15683 A23 I S V K P T L A T S K M T Q L
Sea Urchin Strong. purpuratus XP_790171 172 18920 T32 Q G P V P M V T G L K S A S V
Poplar Tree Populus trichocarpa
Maize Zea mays Q41864 167 18055 V24 G S K D R L L V G N L V L P S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22217 103 11216 D18 F D S A I A Q D K L V V V D F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 56 54.7 N.A. 88.5 87.9 N.A. 27.1 63.8 64.7 56.6 N.A. N.A. 42.1 37.3 39.5
Protein Similarity: 100 N.A. 59.6 58.4 N.A. 93.3 92.1 N.A. 30 68 74.1 71.6 N.A. N.A. 61.4 58.4 60.4
P-Site Identity: 100 N.A. 6.6 0 N.A. 66.6 66.6 N.A. 33.3 6.6 6.6 13.3 N.A. N.A. 0 13.3 26.6
P-Site Similarity: 100 N.A. 6.6 13.3 N.A. 73.3 73.3 N.A. 46.6 13.3 13.3 20 N.A. N.A. 13.3 26.6 40
Percent
Protein Identity: N.A. 29.3 N.A. N.A. 27.7 N.A.
Protein Similarity: N.A. 49.1 N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 20 N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 15 22 8 0 22 15 0 15 0 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 8 0 0 8 0 0 8 0 % D
% Glu: 0 8 0 0 8 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 15 0 0 0 0 0 0 0 8 0 0 8 0 15 8 % F
% Gly: 8 29 8 0 15 8 0 8 15 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % I
% Lys: 8 0 8 8 0 0 0 0 8 8 15 0 0 0 15 % K
% Leu: 8 8 0 22 8 8 43 8 0 22 8 22 8 8 15 % L
% Met: 0 0 0 0 0 8 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 8 8 0 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 8 15 8 36 15 8 0 8 0 0 0 8 8 29 % P
% Gln: 29 8 8 8 0 8 8 8 0 0 0 0 22 8 8 % Q
% Arg: 0 0 8 0 8 8 8 0 0 22 8 8 8 0 8 % R
% Ser: 15 22 8 8 0 29 8 8 29 15 29 22 8 8 15 % S
% Thr: 0 0 8 0 0 15 0 29 8 8 15 8 15 29 0 % T
% Val: 8 8 29 8 0 0 8 8 15 8 8 15 8 0 8 % V
% Trp: 0 0 0 22 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _