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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXN2 All Species: 8.48
Human Site: T34 Identified Species: 14.36
UniProt: Q99757 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99757 NP_036605.2 166 18383 T34 L T S R A L Q T P Q C S P G G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106286 107 12110 T28 P M V V D F H T Q W C G H C K
Dog Lupus familis XP_531748 250 26635 A118 W A P L T C R A L P C S P G H
Cat Felis silvestris
Mouse Mus musculus P97493 166 18237 T34 L T S K T L Q T P Q Y N A G G
Rat Rattus norvegicus P97615 166 18213 T34 L T S T S L Q T P P Y N A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506137 512 55735 G371 L L A R A R P G P A V P P P A
Chicken Gallus gallus NP_001026581 140 15152 I40 R A F G S S A I R G S A F N V
Frog Xenopus laevis NP_001080066 170 18566 L38 N G V R S H G L K A L S S S Q
Zebra Danio Brachydanio rerio NP_991204 166 18440 F33 S S S S R S S F S S C F R A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393603 136 15176 F32 E Q A I S T T F K V Q D P K D
Nematode Worm Caenorhab. elegans Q17424 145 15683 Q29 L A T S K M T Q L R H F S H G
Sea Urchin Strong. purpuratus XP_790171 172 18920 S38 V T G L K S A S V V L V V Q R
Poplar Tree Populus trichocarpa
Maize Zea mays Q41864 167 18055 P30 L V G N L V L P S K R A L A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22217 103 11216 D24 Q D K L V V V D F Y A T W C G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 56 54.7 N.A. 88.5 87.9 N.A. 27.1 63.8 64.7 56.6 N.A. N.A. 42.1 37.3 39.5
Protein Similarity: 100 N.A. 59.6 58.4 N.A. 93.3 92.1 N.A. 30 68 74.1 71.6 N.A. N.A. 61.4 58.4 60.4
P-Site Identity: 100 N.A. 13.3 26.6 N.A. 66.6 60 N.A. 33.3 0 13.3 13.3 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 100 N.A. 13.3 33.3 N.A. 80 73.3 N.A. 40 13.3 20 20 N.A. N.A. 20 33.3 20
Percent
Protein Identity: N.A. 29.3 N.A. N.A. 27.7 N.A.
Protein Similarity: N.A. 49.1 N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 15 0 15 0 15 8 0 15 8 15 15 15 15 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 29 0 0 15 0 % C
% Asp: 0 8 0 0 8 0 0 8 0 0 0 8 0 0 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 15 8 0 0 15 8 0 0 % F
% Gly: 0 8 15 8 0 0 8 8 0 8 0 8 0 29 36 % G
% His: 0 0 0 0 0 8 8 0 0 0 8 0 8 8 8 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 15 0 0 0 15 8 0 0 0 8 8 % K
% Leu: 43 8 0 22 8 22 8 8 15 0 15 0 8 0 0 % L
% Met: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 15 0 8 0 % N
% Pro: 8 0 8 0 0 0 8 8 29 15 0 8 29 8 8 % P
% Gln: 8 8 0 0 0 0 22 8 8 15 8 0 0 8 8 % Q
% Arg: 8 0 0 22 8 8 8 0 8 8 8 0 8 0 8 % R
% Ser: 8 8 29 15 29 22 8 8 15 8 8 22 15 8 0 % S
% Thr: 0 29 8 8 15 8 15 29 0 0 0 8 0 0 0 % T
% Val: 8 8 15 8 8 15 8 0 8 15 8 8 8 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _