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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXN2 All Species: 13.33
Human Site: T43 Identified Species: 22.56
UniProt: Q99757 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99757 NP_036605.2 166 18383 T43 Q C S P G G L T V T P N P A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106286 107 12110 L37 W C G H C K I L G P R L E K M
Dog Lupus familis XP_531748 250 26635 T127 P C S P G H L T A T P T Q A R
Cat Felis silvestris
Mouse Mus musculus P97493 166 18237 T43 Q Y N A G G L T V M P S P A R
Rat Rattus norvegicus P97615 166 18213 T43 P Y N A G G L T G T P S P A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506137 512 55735 R380 A V P P P A A R A L L L R P G
Chicken Gallus gallus NP_001026581 140 15152 D49 G S A F N V Q D G G D F Q E R
Frog Xenopus laevis NP_001080066 170 18566 H47 A L S S S Q I H P H C N L R P
Zebra Danio Brachydanio rerio NP_991204 166 18440 P42 S C F R A A P P L L S R S I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393603 136 15176 N41 V Q D P K D F N N R V K N S K
Nematode Worm Caenorhab. elegans Q17424 145 15683 S38 R H F S H G A S V F D I D S V
Sea Urchin Strong. purpuratus XP_790171 172 18920 P47 V L V V Q R F P Q F I N S S A
Poplar Tree Populus trichocarpa
Maize Zea mays Q41864 167 18055 S39 K R A L A P L S V G R V A T R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22217 103 11216 C33 Y A T W C G P C K M I A P M I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 56 54.7 N.A. 88.5 87.9 N.A. 27.1 63.8 64.7 56.6 N.A. N.A. 42.1 37.3 39.5
Protein Similarity: 100 N.A. 59.6 58.4 N.A. 93.3 92.1 N.A. 30 68 74.1 71.6 N.A. N.A. 61.4 58.4 60.4
P-Site Identity: 100 N.A. 6.6 66.6 N.A. 66.6 60 N.A. 6.6 6.6 13.3 6.6 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 100 N.A. 13.3 66.6 N.A. 80 73.3 N.A. 6.6 13.3 20 13.3 N.A. N.A. 20 33.3 13.3
Percent
Protein Identity: N.A. 29.3 N.A. N.A. 27.7 N.A.
Protein Similarity: N.A. 49.1 N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. 20 N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. 40 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 15 15 15 15 15 0 15 0 0 8 8 29 8 % A
% Cys: 0 29 0 0 15 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 8 0 0 15 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 15 8 0 0 15 0 0 15 0 8 0 0 0 % F
% Gly: 8 0 8 0 29 36 0 0 22 15 0 0 0 0 8 % G
% His: 0 8 0 8 8 8 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 15 8 0 8 8 % I
% Lys: 8 0 0 0 8 8 0 0 8 0 0 8 0 8 8 % K
% Leu: 0 15 0 8 0 0 36 8 8 15 8 15 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 0 0 8 8 % M
% Asn: 0 0 15 0 8 0 0 8 8 0 0 22 8 0 0 % N
% Pro: 15 0 8 29 8 8 15 15 8 8 29 0 29 8 15 % P
% Gln: 15 8 0 0 8 8 8 0 8 0 0 0 15 0 0 % Q
% Arg: 8 8 0 8 0 8 0 8 0 8 15 8 8 8 43 % R
% Ser: 8 8 22 15 8 0 0 15 0 0 8 15 15 22 0 % S
% Thr: 0 0 8 0 0 0 0 29 0 22 0 8 0 8 0 % T
% Val: 15 8 8 8 0 8 0 0 29 0 8 8 0 0 8 % V
% Trp: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _