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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXN2
All Species:
4.85
Human Site:
Y53
Identified Species:
8.21
UniProt:
Q99757
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99757
NP_036605.2
166
18383
Y53
P
N
P
A
R
T
I
Y
T
T
R
I
S
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106286
107
12110
K47
R
L
E
K
M
V
A
K
Q
H
R
K
V
L
M
Dog
Lupus familis
XP_531748
250
26635
Y137
P
T
Q
A
R
S
I
Y
T
T
R
V
C
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P97493
166
18237
H53
P
S
P
A
R
T
V
H
T
T
R
V
C
L
T
Rat
Rattus norvegicus
P97615
166
18213
H53
P
S
P
A
R
T
F
H
T
T
R
V
C
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506137
512
55735
A390
L
L
R
P
G
P
P
A
P
R
L
S
A
R
T
Chicken
Gallus gallus
NP_001026581
140
15152
N59
D
F
Q
E
R
V
V
N
S
P
K
P
V
V
V
Frog
Xenopus laevis
NP_001080066
170
18566
T57
C
N
L
R
P
I
S
T
S
T
P
C
R
V
T
Zebra Danio
Brachydanio rerio
NP_991204
166
18440
P52
S
R
S
I
P
R
L
P
Y
I
T
S
R
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393603
136
15176
V51
V
K
N
S
K
V
P
V
I
V
D
F
F
A
T
Nematode Worm
Caenorhab. elegans
Q17424
145
15683
F48
D
I
D
S
V
E
D
F
T
E
K
V
I
Q
S
Sea Urchin
Strong. purpuratus
XP_790171
172
18920
H57
I
N
S
S
A
P
F
H
S
S
S
H
C
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41864
167
18055
R49
R
V
A
T
R
R
P
R
H
V
C
Q
S
K
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22217
103
11216
F43
I
A
P
M
I
E
K
F
S
E
Q
Y
P
Q
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
56
54.7
N.A.
88.5
87.9
N.A.
27.1
63.8
64.7
56.6
N.A.
N.A.
42.1
37.3
39.5
Protein Similarity:
100
N.A.
59.6
58.4
N.A.
93.3
92.1
N.A.
30
68
74.1
71.6
N.A.
N.A.
61.4
58.4
60.4
P-Site Identity:
100
N.A.
13.3
60
N.A.
66.6
60
N.A.
6.6
6.6
20
0
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
13.3
73.3
N.A.
93.3
80
N.A.
13.3
33.3
33.3
6.6
N.A.
N.A.
20
40
40
Percent
Protein Identity:
N.A.
29.3
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
49.1
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
29
8
0
8
8
0
0
0
0
8
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
8
29
0
0
% C
% Asp:
15
0
8
0
0
0
8
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
8
8
0
15
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
15
15
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
22
8
8
0
8
0
0
0
% H
% Ile:
15
8
0
8
8
8
15
0
8
8
0
8
8
0
0
% I
% Lys:
0
8
0
8
8
0
8
8
0
0
15
8
0
8
0
% K
% Leu:
8
15
8
0
0
0
8
0
0
0
8
0
0
29
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
22
8
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
29
0
29
8
15
15
22
8
8
8
8
8
8
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
8
0
8
8
0
15
0
% Q
% Arg:
15
8
8
8
43
15
0
8
0
8
36
0
15
8
0
% R
% Ser:
8
15
15
22
0
8
8
0
29
8
8
15
15
15
8
% S
% Thr:
0
8
0
8
0
22
0
8
36
36
8
0
0
8
50
% T
% Val:
8
8
0
0
8
22
15
8
0
15
0
29
15
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _