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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA3 All Species: 13.03
Human Site: S339 Identified Species: 28.67
UniProt: Q99758 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99758 NP_001080.2 1704 191362 S339 K P N V A V L S R S D P S L V
Chimpanzee Pan troglodytes XP_510744 1704 191477 S339 K P N V A V L S R S D P S L V
Rhesus Macaque Macaca mulatta XP_001085237 1692 190227 S339 K P D V A V L S R S D P S L V
Dog Lupus familis XP_537004 1758 196286 P395 V P L N T D S P S L L I A V L
Cat Felis silvestris
Mouse Mus musculus Q8R420 1704 191982 S339 K K D I A V L S N S D P S L V
Rat Rattus norvegicus Q9ESR9 2434 270910 M778 L K Y G Q V L M H S H V L I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414701 1641 183766 R328 P Y F F I S P R Y D L M S H S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661144 1343 149621 A95 I G L L L L D A L L Y G L V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 L336 E F V S P A A L I V T V L M Y
Sea Urchin Strong. purpuratus XP_791165 1668 186656 K343 G P Q G A I F K S S E P T V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 K349 C T M G S L F K Y S D K T L V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 85.1 N.A. 87.9 28.6 N.A. N.A. 66.3 N.A. 51.4 N.A. N.A. N.A. 28.2 44.5
Protein Similarity: 100 99.7 97.2 90.6 N.A. 94.2 43.3 N.A. N.A. 79.2 N.A. 62 N.A. N.A. N.A. 48.4 63.3
P-Site Identity: 100 100 93.3 6.6 N.A. 73.3 20 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. 0 26.6
P-Site Similarity: 100 100 100 26.6 N.A. 86.6 33.3 N.A. N.A. 6.6 N.A. 26.6 N.A. N.A. N.A. 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. 30.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 46 10 10 10 0 0 0 0 10 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 19 0 0 10 10 0 0 10 46 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 10 10 10 0 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 28 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 10 0 0 10 0 % H
% Ile: 10 0 0 10 10 10 0 0 10 0 0 10 0 10 19 % I
% Lys: 37 19 0 0 0 0 0 19 0 0 0 10 0 0 0 % K
% Leu: 10 0 19 10 10 19 46 10 10 19 19 0 28 46 10 % L
% Met: 0 0 10 0 0 0 0 10 0 0 0 10 0 10 0 % M
% Asn: 0 0 19 10 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 10 46 0 0 10 0 10 10 0 0 0 46 0 0 0 % P
% Gln: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 28 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 10 10 10 37 19 64 0 0 46 0 10 % S
% Thr: 0 10 0 0 10 0 0 0 0 0 10 0 19 0 0 % T
% Val: 10 0 10 28 0 46 0 0 0 10 0 19 0 28 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 19 0 10 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _