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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA3 All Species: 17.88
Human Site: S712 Identified Species: 39.33
UniProt: Q99758 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99758 NP_001080.2 1704 191362 S712 D L L Q R Q K S D R T I V L T
Chimpanzee Pan troglodytes XP_510744 1704 191477 S712 D L L Q R Q K S D R T I V L T
Rhesus Macaque Macaca mulatta XP_001085237 1692 190227 S712 D L L Q R Q K S D R T I V L T
Dog Lupus familis XP_537004 1758 196286 S766 D L L Q Q H K S D R T V L L T
Cat Felis silvestris
Mouse Mus musculus Q8R420 1704 191982 S712 D L L Q Q Q K S D R T V L L T
Rat Rattus norvegicus Q9ESR9 2434 270910 P1170 D L I L K Y K P G R T I L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414701 1641 183766 L663 F M D E A D L L G D R I A I M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661144 1343 149621 L430 E S S A G A E L S Y I L P K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 A726 K L V E R E K A N R T I L L T
Sea Urchin Strong. purpuratus XP_791165 1668 186656 K714 D L L Q Q H R K G R T M I L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 K731 Q L I K K I K K G R I I L L T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 85.1 N.A. 87.9 28.6 N.A. N.A. 66.3 N.A. 51.4 N.A. N.A. N.A. 28.2 44.5
Protein Similarity: 100 99.7 97.2 90.6 N.A. 94.2 43.3 N.A. N.A. 79.2 N.A. 62 N.A. N.A. N.A. 48.4 63.3
P-Site Identity: 100 100 100 73.3 N.A. 80 46.6 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. 53.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 73.3 N.A. N.A. 26.6 N.A. 20 N.A. N.A. N.A. 93.3 80
Percent
Protein Identity: N.A. N.A. N.A. 30.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 10 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 64 0 10 0 0 10 0 0 46 10 0 0 0 0 0 % D
% Glu: 10 0 0 19 0 10 10 0 0 0 0 0 0 0 10 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 37 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 10 0 0 0 0 19 64 10 10 0 % I
% Lys: 10 0 0 10 19 0 73 19 0 0 0 0 0 10 0 % K
% Leu: 0 82 55 10 0 0 10 19 0 0 0 10 46 82 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % P
% Gln: 10 0 0 55 28 37 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 37 0 10 0 0 82 10 0 0 0 0 % R
% Ser: 0 10 10 0 0 0 0 46 10 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 73 0 0 0 73 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 19 28 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _