KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBA2
All Species:
16.36
Human Site:
S275
Identified Species:
40
UniProt:
Q99767
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99767
NP_001123886.1
749
82512
S275
I
K
A
S
C
S
P
S
R
H
E
A
R
P
K
Chimpanzee
Pan troglodytes
XP_001163875
749
82639
S275
I
K
A
S
C
S
P
S
R
H
E
A
R
P
K
Rhesus Macaque
Macaca mulatta
XP_001109622
748
82268
S275
I
K
A
S
C
S
P
S
R
H
E
A
R
P
K
Dog
Lupus familis
XP_848698
754
82260
S280
C
E
A
S
H
G
P
S
R
H
E
G
R
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P98084
750
82740
G276
S
D
T
G
H
G
P
G
R
Q
E
A
R
P
K
Rat
Rattus norvegicus
O35431
750
82832
S276
S
D
T
G
R
G
P
S
R
Q
E
A
R
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511424
661
70312
E236
P
A
G
P
E
G
P
E
A
G
G
G
D
L
Q
Chicken
Gallus gallus
XP_413771
755
83894
N281
G
E
A
V
H
S
A
N
R
H
E
G
R
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17583
982
105225
P475
P
P
P
S
H
P
I
P
R
R
V
S
G
N
G
Sea Urchin
Strong. purpuratus
XP_001184612
1518
170192
S383
D
K
K
S
E
I
L
S
L
D
I
L
Q
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.5
90.8
N.A.
92.4
92.2
N.A.
44.5
81.7
N.A.
N.A.
N.A.
N.A.
N.A.
33.9
29.4
Protein Similarity:
100
99.1
98
92.3
N.A.
93.8
93.7
N.A.
57.5
87.6
N.A.
N.A.
N.A.
N.A.
N.A.
47.7
38.1
P-Site Identity:
100
100
100
66.6
N.A.
46.6
53.3
N.A.
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
100
100
73.3
N.A.
46.6
53.3
N.A.
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
50
0
0
0
10
0
10
0
0
50
0
0
0
% A
% Cys:
10
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
0
0
0
0
0
0
0
10
0
0
10
10
0
% D
% Glu:
0
20
0
0
20
0
0
10
0
0
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
20
0
40
0
10
0
10
10
30
10
0
10
% G
% His:
0
0
0
0
40
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
30
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% I
% Lys:
0
40
10
0
0
0
0
0
0
0
0
0
0
0
70
% K
% Leu:
0
0
0
0
0
0
10
0
10
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
20
10
10
10
0
10
70
10
0
0
0
0
0
70
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
10
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
80
10
0
0
70
0
10
% R
% Ser:
20
0
0
60
0
40
0
60
0
0
0
10
0
0
0
% S
% Thr:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _