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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBA2
All Species:
20.61
Human Site:
Y186
Identified Species:
50.37
UniProt:
Q99767
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99767
NP_001123886.1
749
82512
Y186
D
Q
E
E
D
G
H
Y
C
A
S
K
E
G
Y
Chimpanzee
Pan troglodytes
XP_001163875
749
82639
Y186
D
Q
E
E
D
G
H
Y
C
A
S
K
E
G
Y
Rhesus Macaque
Macaca mulatta
XP_001109622
748
82268
Y186
D
Q
E
E
D
G
H
Y
C
P
S
K
E
G
Y
Dog
Lupus familis
XP_848698
754
82260
Y186
D
Q
E
E
G
V
H
Y
C
P
S
E
E
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
P98084
750
82740
Y186
D
Q
E
E
D
G
H
Y
C
S
S
K
E
S
Y
Rat
Rattus norvegicus
O35431
750
82832
Y186
D
Q
E
E
D
G
H
Y
C
P
S
K
E
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511424
661
70312
P158
P
R
E
G
L
P
C
P
L
H
I
A
M
G
R
Chicken
Gallus gallus
XP_413771
755
83894
N187
E
I
Q
D
Q
D
E
N
I
Q
Y
C
Q
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17583
982
105225
P359
P
I
G
V
T
M
T
P
Q
A
T
F
G
A
A
Sea Urchin
Strong. purpuratus
XP_001184612
1518
170192
F299
E
S
K
E
D
G
K
F
E
E
E
E
E
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.5
90.8
N.A.
92.4
92.2
N.A.
44.5
81.7
N.A.
N.A.
N.A.
N.A.
N.A.
33.9
29.4
Protein Similarity:
100
99.1
98
92.3
N.A.
93.8
93.7
N.A.
57.5
87.6
N.A.
N.A.
N.A.
N.A.
N.A.
47.7
38.1
P-Site Identity:
100
100
93.3
73.3
N.A.
86.6
86.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
86.6
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
30
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
60
0
0
10
0
0
0
% C
% Asp:
60
0
0
10
60
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
70
70
0
0
10
0
10
10
10
20
70
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
10
10
10
60
0
0
0
0
0
0
10
50
0
% G
% His:
0
0
0
0
0
0
60
0
0
10
0
0
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
50
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
20
0
0
0
0
10
0
20
0
30
0
0
0
0
0
% P
% Gln:
0
60
10
0
10
0
0
0
10
10
0
0
10
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
0
0
0
0
0
10
60
0
0
30
0
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
10
0
0
0
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _