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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIPEP All Species: 11.82
Human Site: S480 Identified Species: 20
UniProt: Q99797 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99797 NP_005923.2 713 80641 S480 N L P R S S R S S P T L L T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090198 713 80564 S480 N L P R S S R S S P T L L T P
Dog Lupus familis XP_534532 662 75720 N429 N L P H S S R N S P T L L T P
Cat Felis silvestris
Mouse Mus musculus A6H611 711 80834 D478 N L P H A S R D F P T L L T P
Rat Rattus norvegicus Q01992 710 80655 D477 N L P H A S R D F P T L L T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519255 686 77419 N453 S L P H S T R N S P T L L T P
Chicken Gallus gallus XP_417136 704 79533 N472 S L P H S T R N A P T L L S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344847 700 79903 A467 N L P H P T R A S P T L L S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610183 699 80218 S462 G L A Q P R W S G P T L L S P
Honey Bee Apis mellifera XP_396237 696 80078 S464 S L P V P T W S K P C L L S P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182998 420 47731 E204 K F V S L N E E L L M L G S Y
Poplar Tree Populus trichocarpa XP_002321840 726 81749 S491 N F S G S P G S S T V R L N H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35999 772 88164 K543 P I L I A S K K S L C F L Q L
Red Bread Mold Neurospora crassa Q7SDD5 805 91077 N563 D F P Q Q S H N R P A L L S F
Conservation
Percent
Protein Identity: 100 N.A. 97.9 85.6 N.A. 82.8 83.4 N.A. 77 78.6 N.A. 71.3 N.A. 47.5 46 N.A. 29.1
Protein Similarity: 100 N.A. 98.8 89.4 N.A. 90 89.1 N.A. 85.5 88.5 N.A. 84.4 N.A. 65.7 66 N.A. 43
P-Site Identity: 100 N.A. 100 86.6 N.A. 73.3 73.3 N.A. 73.3 60 N.A. 66.6 N.A. 46.6 46.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 80 80 N.A. 93.3 93.3 N.A. 86.6 N.A. 60 66.6 N.A. 20
Percent
Protein Identity: 34.5 N.A. N.A. N.A. 31.3 29.8
Protein Similarity: 53.8 N.A. N.A. N.A. 50.9 46
P-Site Identity: 33.3 N.A. N.A. N.A. 20 33.3
P-Site Similarity: 33.3 N.A. N.A. N.A. 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 22 0 0 8 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % E
% Phe: 0 22 0 0 0 0 0 0 15 0 0 8 0 0 8 % F
% Gly: 8 0 0 8 0 0 8 0 8 0 0 0 8 0 0 % G
% His: 0 0 0 43 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 8 8 8 0 0 0 0 0 0 % K
% Leu: 0 72 8 0 8 0 0 0 8 15 0 86 93 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 50 0 0 0 0 8 0 29 0 0 0 0 0 8 0 % N
% Pro: 8 0 72 0 22 8 0 0 0 79 0 0 0 0 72 % P
% Gln: 0 0 0 15 8 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 15 0 8 58 0 8 0 0 8 0 0 0 % R
% Ser: 22 0 8 8 43 50 0 36 50 0 0 0 0 43 0 % S
% Thr: 0 0 0 0 0 29 0 0 0 8 65 0 0 43 0 % T
% Val: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _