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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIPEP All Species: 26.36
Human Site: S559 Identified Species: 44.62
UniProt: Q99797 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99797 NP_005923.2 713 80641 S559 P L P K N M V S R L C E S K K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090198 713 80564 S559 P L P K N M V S R L C E S K K
Dog Lupus familis XP_534532 662 75720 S508 S L P K S M V S R L C E S K K
Cat Felis silvestris
Mouse Mus musculus A6H611 711 80834 S557 P L P K A M V S R L C E S K K
Rat Rattus norvegicus Q01992 710 80655 S556 P L P K A M V S R L C E S K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519255 686 77419 S532 P L P K S M V S R L C E S K K
Chicken Gallus gallus XP_417136 704 79533 S551 P L P K N M V S R L C E S K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344847 700 79903 A546 P L P Q S M V A R L C E S K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610183 699 80218 R541 P I S E D M L R R L C A S K N
Honey Bee Apis mellifera XP_396237 696 80078 D543 Q I P I T L L D K L Y A S K N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182998 420 47731 H283 D R L L A G R H E L A N L V E
Poplar Tree Populus trichocarpa XP_002321840 726 81749 K570 I I P E K L V K S M Q G A R D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35999 772 88164 Q622 T I Q A D M L Q R F M K S T N
Red Bread Mold Neurospora crassa Q7SDD5 805 91077 D642 P L P Y E W V D N K I R E A R
Conservation
Percent
Protein Identity: 100 N.A. 97.9 85.6 N.A. 82.8 83.4 N.A. 77 78.6 N.A. 71.3 N.A. 47.5 46 N.A. 29.1
Protein Similarity: 100 N.A. 98.8 89.4 N.A. 90 89.1 N.A. 85.5 88.5 N.A. 84.4 N.A. 65.7 66 N.A. 43
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 93.3 100 N.A. 80 N.A. 46.6 26.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 100 100 N.A. 100 N.A. 73.3 53.3 N.A. 13.3
Percent
Protein Identity: 34.5 N.A. N.A. N.A. 31.3 29.8
Protein Similarity: 53.8 N.A. N.A. N.A. 50.9 46
P-Site Identity: 13.3 N.A. N.A. N.A. 20 26.6
P-Site Similarity: 53.3 N.A. N.A. N.A. 46.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 22 0 0 8 0 0 8 15 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 65 0 0 0 0 % C
% Asp: 8 0 0 0 15 0 0 15 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 15 8 0 0 0 8 0 0 58 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 29 0 8 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 50 8 0 0 8 8 8 0 8 0 72 58 % K
% Leu: 0 65 8 8 0 15 22 0 0 79 0 0 8 0 0 % L
% Met: 0 0 0 0 0 72 0 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 22 0 0 0 8 0 0 8 0 0 22 % N
% Pro: 65 0 79 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 8 8 0 0 0 8 0 0 8 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 8 8 72 0 0 8 0 8 8 % R
% Ser: 8 0 8 0 22 0 0 50 8 0 0 0 79 0 0 % S
% Thr: 8 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 72 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _