KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO2
All Species:
17.27
Human Site:
S551
Identified Species:
27.14
UniProt:
Q99798
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99798
NP_001089.1
780
85425
S551
Y
Q
H
P
P
K
D
S
S
G
Q
H
V
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105023
780
85329
S551
Y
Q
H
P
P
K
D
S
S
G
Q
H
V
D
V
Dog
Lupus familis
XP_849166
781
85703
S551
Y
Q
H
P
P
K
D
S
S
G
Q
R
V
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI0
780
85445
S551
Y
Q
H
P
P
K
D
S
S
G
Q
R
V
D
V
Rat
Rattus norvegicus
Q9ER34
780
85415
S551
Y
Q
H
P
P
K
D
S
S
G
Q
R
V
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516809
792
86180
G562
Y
Q
Y
P
P
K
D
G
S
S
Q
R
V
D
V
Chicken
Gallus gallus
Q90875
889
98055
P629
A
W
N
A
L
D
A
P
S
D
K
L
Y
T
W
Frog
Xenopus laevis
NP_001086263
782
85257
G553
Y
Q
H
P
P
I
D
G
S
S
L
N
V
D
V
Zebra Danio
Brachydanio rerio
NP_944590
782
84841
G553
Y
Q
H
P
P
A
D
G
S
A
L
K
V
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524708
787
85380
G559
Y
T
A
P
P
P
S
G
E
N
V
K
V
A
V
Honey Bee
Apis mellifera
XP_391994
788
85977
G557
Y
D
A
P
P
A
D
G
S
S
V
K
V
D
V
Nematode Worm
Caenorhab. elegans
P34455
777
84028
G548
F
Q
A
P
S
G
S
G
Q
V
D
V
S
P
S
Sea Urchin
Strong. purpuratus
XP_001176556
783
84215
G553
F
Q
P
P
P
S
D
G
S
G
I
A
V
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
A633
M
W
N
Q
L
S
V
A
S
G
T
L
Y
E
W
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
R548
Y
Q
A
P
P
A
D
R
S
T
V
E
V
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
96.4
N.A.
96.7
96.4
N.A.
89.5
26.5
87.4
82.9
N.A.
70.9
73.4
73
74.4
Protein Similarity:
100
N.A.
99.4
98.5
N.A.
98.8
98.5
N.A.
93.8
44.4
93.9
90.6
N.A.
81.4
83.8
83.2
85.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
73.3
6.6
66.6
66.6
N.A.
33.3
53.3
13.3
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
80
20
73.3
66.6
N.A.
33.3
53.3
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.2
65.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.5
79.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
27
7
0
20
7
7
0
7
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
74
0
0
7
7
0
0
67
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
0
% E
% Phe:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
47
0
47
0
0
0
0
0
% G
% His:
0
0
47
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
40
0
0
0
0
7
20
0
7
0
% K
% Leu:
0
0
0
0
14
0
0
0
0
0
14
14
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
14
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
7
87
80
7
0
7
0
0
0
0
0
7
0
% P
% Gln:
0
74
0
7
0
0
0
0
7
0
40
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
27
0
0
0
% R
% Ser:
0
0
0
0
7
14
14
34
87
20
0
0
7
0
7
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
7
0
0
7
0
% T
% Val:
0
0
0
0
0
0
7
0
0
7
20
7
80
0
80
% V
% Trp:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
14
% W
% Tyr:
74
0
7
0
0
0
0
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _