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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACO2 All Species: 52.42
Human Site: S87 Identified Species: 82.38
UniProt: Q99798 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99798 NP_001089.1 780 85425 S87 Q E I E R G K S Y L R L R P D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105023 780 85329 S87 Q E I E R G K S Y L R L R P D
Dog Lupus familis XP_849166 781 85703 T87 Q D I E R G K T Y L R L R P D
Cat Felis silvestris
Mouse Mus musculus Q99KI0 780 85445 T87 Q E I E R G K T Y L R L R P D
Rat Rattus norvegicus Q9ER34 780 85415 T87 Q E I E R G K T Y L R L R P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516809 792 86180 T98 Q E I E R G K T Y L R L R P D
Chicken Gallus gallus Q90875 889 98055 E112 K K L G G D P E K I N P I C P
Frog Xenopus laevis NP_001086263 782 85257 T89 Q E I V R G K T Y L R L R P D
Zebra Danio Brachydanio rerio NP_944590 782 84841 T89 Q E I A R G R T Y L R L R P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524708 787 85380 S94 Q D I V R G T S Y L R L R P D
Honey Bee Apis mellifera XP_391994 788 85977 T92 Q E I Q R G T T Y L R L R P D
Nematode Worm Caenorhab. elegans P34455 777 84028 S84 Q D I E R G V S Y L R L R P D
Sea Urchin Strong. purpuratus XP_001176556 783 84215 S89 Q D I E R G E S Y L K L R P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42560 898 98134 N116 N N L G G D S N K I N P L V P
Baker's Yeast Sacchar. cerevisiae P19414 778 85350 S83 Q D I Q R G V S Y L K L R P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.9 96.4 N.A. 96.7 96.4 N.A. 89.5 26.5 87.4 82.9 N.A. 70.9 73.4 73 74.4
Protein Similarity: 100 N.A. 99.4 98.5 N.A. 98.8 98.5 N.A. 93.8 44.4 93.9 90.6 N.A. 81.4 83.8 83.2 85.7
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 93.3 0 86.6 80 N.A. 80 80 86.6 80
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 26.6 93.3 93.3 N.A. 86.6 93.3 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. 27.2 65.7 N.A.
Protein Similarity: N.A. N.A. N.A. 43.5 79.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 34 0 0 0 14 0 0 0 0 0 0 0 0 87 % D
% Glu: 0 54 0 54 0 0 7 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 14 14 87 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 87 0 0 0 0 0 0 14 0 0 7 0 0 % I
% Lys: 7 7 0 0 0 0 47 0 14 0 14 0 0 0 0 % K
% Leu: 0 0 14 0 0 0 0 0 0 87 0 87 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 7 0 0 14 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 14 0 87 14 % P
% Gln: 87 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 87 0 7 0 0 0 74 0 87 0 0 % R
% Ser: 0 0 0 0 0 0 7 40 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 14 47 0 0 0 0 0 0 0 % T
% Val: 0 0 0 14 0 0 14 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _