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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO2
All Species:
41.52
Human Site:
T515
Identified Species:
65.24
UniProt:
Q99798
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99798
NP_001089.1
780
85425
T515
N
P
E
T
D
Y
L
T
G
T
D
G
K
K
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105023
780
85329
T515
N
P
E
T
D
Y
L
T
G
T
D
G
K
K
F
Dog
Lupus familis
XP_849166
781
85703
T515
N
P
E
T
D
F
L
T
G
K
D
G
K
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI0
780
85445
T515
N
P
E
T
D
F
L
T
G
K
D
G
K
K
F
Rat
Rattus norvegicus
Q9ER34
780
85415
T515
N
P
E
T
D
F
L
T
G
K
D
G
K
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516809
792
86180
T526
N
P
E
T
D
F
L
T
G
K
D
G
K
K
F
Chicken
Gallus gallus
Q90875
889
98055
G576
D
F
E
K
E
P
L
G
I
S
A
S
G
K
K
Frog
Xenopus laevis
NP_001086263
782
85257
T517
D
P
E
R
D
F
L
T
G
A
D
G
K
K
F
Zebra Danio
Brachydanio rerio
NP_944590
782
84841
T517
N
P
E
T
D
Y
L
T
A
P
N
G
E
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524708
787
85380
T523
N
P
L
T
D
E
L
T
G
A
D
G
K
K
F
Honey Bee
Apis mellifera
XP_391994
788
85977
K521
N
P
V
T
D
K
L
K
A
K
D
G
K
E
F
Nematode Worm
Caenorhab. elegans
P34455
777
84028
T512
N
P
L
T
D
E
L
T
A
A
D
G
S
K
F
Sea Urchin
Strong. purpuratus
XP_001176556
783
84215
T517
D
P
E
V
D
E
L
T
G
A
N
G
Q
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
T581
F
E
T
Q
P
I
G
T
G
K
D
G
K
Q
I
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
K512
N
P
L
T
D
K
L
K
D
K
D
G
N
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
96.4
N.A.
96.7
96.4
N.A.
89.5
26.5
87.4
82.9
N.A.
70.9
73.4
73
74.4
Protein Similarity:
100
N.A.
99.4
98.5
N.A.
98.8
98.5
N.A.
93.8
44.4
93.9
90.6
N.A.
81.4
83.8
83.2
85.7
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
86.6
20
73.3
73.3
N.A.
80
60
66.6
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
93.3
40
86.6
86.6
N.A.
80
66.6
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.2
65.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.5
79.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
27
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
87
0
0
0
7
0
80
0
0
0
0
% D
% Glu:
0
7
67
0
7
20
0
0
0
0
0
0
7
14
0
% E
% Phe:
7
7
0
0
0
34
0
0
0
0
0
0
0
0
87
% F
% Gly:
0
0
0
0
0
0
7
7
67
0
0
94
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% I
% Lys:
0
0
0
7
0
14
0
14
0
47
0
0
67
80
7
% K
% Leu:
0
0
20
0
0
0
94
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
74
0
0
0
0
0
0
0
0
0
14
0
7
0
0
% N
% Pro:
0
87
0
0
7
7
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% S
% Thr:
0
0
7
74
0
0
0
80
0
14
0
0
0
0
0
% T
% Val:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _