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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO2
All Species:
51.82
Human Site:
Y650
Identified Species:
81.43
UniProt:
Q99798
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99798
NP_001089.1
780
85425
Y650
V
P
D
T
A
R
Y
Y
K
K
H
G
I
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105023
780
85329
Y650
V
P
D
T
A
R
Y
Y
K
K
H
G
I
R
W
Dog
Lupus familis
XP_849166
781
85703
Y650
V
P
D
T
A
R
Y
Y
K
K
H
G
I
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI0
780
85445
Y650
V
P
D
T
A
R
Y
Y
K
K
H
G
I
R
W
Rat
Rattus norvegicus
Q9ER34
780
85415
Y650
V
P
D
T
A
R
Y
Y
K
K
H
G
I
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516809
792
86180
Y661
V
P
D
T
A
R
Y
Y
K
K
N
G
I
K
W
Chicken
Gallus gallus
Q90875
889
98055
Y759
V
F
D
A
A
E
R
Y
K
Q
A
G
H
P
L
Frog
Xenopus laevis
NP_001086263
782
85257
Y652
V
P
D
T
A
R
Y
Y
K
A
H
G
I
K
W
Zebra Danio
Brachydanio rerio
NP_944590
782
84841
Y652
V
P
D
V
A
R
H
Y
K
K
N
N
I
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524708
787
85380
Y658
V
P
D
V
A
R
D
Y
K
A
N
G
I
K
W
Honey Bee
Apis mellifera
XP_391994
788
85977
Y656
V
P
D
V
A
R
H
Y
K
K
N
G
V
K
W
Nematode Worm
Caenorhab. elegans
P34455
777
84028
Y644
V
P
A
T
A
R
K
Y
K
A
D
G
V
R
W
Sea Urchin
Strong. purpuratus
XP_001176556
783
84215
Y651
V
P
A
T
A
R
D
Y
K
S
K
N
T
P
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
Y764
V
F
D
A
A
M
K
Y
R
N
E
G
R
D
T
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
Y647
V
P
D
T
A
R
D
Y
R
D
Q
G
I
K
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
96.4
N.A.
96.7
96.4
N.A.
89.5
26.5
87.4
82.9
N.A.
70.9
73.4
73
74.4
Protein Similarity:
100
N.A.
99.4
98.5
N.A.
98.8
98.5
N.A.
93.8
44.4
93.9
90.6
N.A.
81.4
83.8
83.2
85.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
40
86.6
66.6
N.A.
66.6
66.6
66.6
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
46.6
93.3
80
N.A.
80
93.3
73.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.2
65.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.5
79.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
100
0
0
0
0
20
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
87
0
0
0
20
0
0
7
7
0
0
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
87
0
0
0
% G
% His:
0
0
0
0
0
0
14
0
0
0
40
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% I
% Lys:
0
0
0
0
0
0
14
0
87
54
7
0
0
34
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
27
14
0
0
0
% N
% Pro:
0
87
0
0
0
0
0
0
0
0
0
0
0
14
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
87
7
0
14
0
0
0
7
40
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% S
% Thr:
0
0
0
67
0
0
0
0
0
0
0
0
7
0
7
% T
% Val:
100
0
0
20
0
0
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
87
% W
% Tyr:
0
0
0
0
0
0
47
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _