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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
10.91
Human Site:
S110
Identified Species:
20
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
S110
L
L
D
S
E
N
T
S
G
A
L
P
R
L
P
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
S105
L
S
D
C
E
N
T
S
G
A
L
P
R
L
P
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
S108
L
L
D
C
E
N
T
S
G
S
L
P
S
L
P
Dog
Lupus familis
XP_543240
206
23431
G83
L
D
C
E
N
S
A
G
S
L
P
S
L
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
P111
L
L
D
C
E
H
N
P
G
D
L
A
S
A
P
Rat
Rattus norvegicus
P23441
372
38536
G147
M
G
G
L
G
S
L
G
D
V
S
K
N
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
T397
Y
L
L
N
C
E
N
T
P
S
A
F
P
G
L
Chicken
Gallus gallus
Q90788
294
33054
K105
H
K
S
L
E
Q
E
K
R
E
L
E
D
P
E
Frog
Xenopus laevis
Q9W7E8
213
24704
I90
E
L
D
T
A
Q
P
I
T
A
V
E
N
K
L
Zebra Danio
Brachydanio rerio
Q90481
269
30288
N111
S
A
D
E
S
P
D
N
D
K
E
T
S
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
S161
P
P
L
S
S
S
P
S
E
S
P
L
S
H
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
S136
C
S
I
D
P
V
R
S
A
I
N
H
Q
F
S
Sea Urchin
Strong. purpuratus
Q26656
405
44721
E239
R
R
N
N
G
H
E
E
D
D
D
D
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
86.6
80
6.6
N.A.
46.6
0
N.A.
6.6
13.3
20
6.6
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
86.6
86.6
13.3
N.A.
53.3
20
N.A.
26.6
13.3
33.3
13.3
N.A.
26.6
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
0
8
24
8
8
0
8
8
% A
% Cys:
8
0
8
24
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
47
8
0
0
8
0
24
16
8
8
16
8
16
% D
% Glu:
8
0
0
16
39
8
16
8
8
8
8
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
8
8
0
16
0
0
16
31
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
16
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
8
0
8
0
8
0
% K
% Leu:
39
39
16
16
0
0
8
0
0
8
39
8
8
24
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
16
8
24
16
8
0
0
8
0
16
0
8
% N
% Pro:
8
8
0
0
8
8
16
8
8
0
16
24
8
16
31
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
8
% Q
% Arg:
8
8
0
0
0
0
8
0
8
0
0
0
16
0
0
% R
% Ser:
8
16
8
16
16
24
0
39
8
24
8
8
31
8
8
% S
% Thr:
0
0
0
8
0
0
24
8
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _