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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
10
Human Site:
S48
Identified Species:
18.33
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
S48
R
Q
G
G
R
T
S
S
Q
R
Q
R
D
P
E
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
S47
Q
R
Q
G
G
R
T
S
S
Q
R
Q
R
D
P
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
S48
R
R
G
G
H
T
D
S
P
R
R
R
D
P
E
Dog
Lupus familis
XP_543240
206
23431
W25
L
R
V
G
T
G
I
W
G
G
I
V
W
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
N52
R
H
G
G
H
S
G
N
P
Q
H
S
P
D
P
Rat
Rattus norvegicus
P23441
372
38536
A51
G
Q
A
A
P
P
A
A
A
M
Q
Q
H
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
F296
R
R
T
G
P
K
A
F
P
R
S
R
E
N
P
Chicken
Gallus gallus
Q90788
294
33054
F42
P
S
C
M
L
A
T
F
K
Q
E
A
F
G
S
Frog
Xenopus laevis
Q9W7E8
213
24704
S32
L
S
H
M
G
P
G
S
K
E
K
S
L
G
F
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Q49
K
T
P
G
V
L
V
Q
S
P
L
E
N
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
S56
P
E
K
L
K
P
S
S
D
R
E
R
S
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
A70
Q
Q
L
L
K
M
A
A
S
K
S
G
T
P
G
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S98
R
S
P
P
M
S
P
S
S
P
S
M
S
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
13.3
66.6
6.6
N.A.
20
13.3
N.A.
26.6
0
6.6
6.6
N.A.
26.6
N.A.
13.3
13.3
P-Site Similarity:
100
53.3
80
13.3
N.A.
40
33.3
N.A.
46.6
26.6
20
26.6
N.A.
46.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
24
16
8
0
0
8
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
0
0
0
16
16
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
16
8
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
8
% F
% Gly:
8
0
24
54
16
8
16
0
8
8
0
8
0
24
8
% G
% His:
0
8
8
0
16
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% I
% Lys:
8
0
8
0
16
8
0
0
16
8
8
0
0
0
0
% K
% Leu:
16
0
8
16
8
8
0
0
0
0
8
0
8
0
0
% L
% Met:
0
0
0
16
8
8
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
8
% N
% Pro:
16
0
16
8
16
24
8
0
24
16
0
0
8
24
24
% P
% Gln:
16
24
8
0
0
0
0
8
8
24
16
16
0
0
8
% Q
% Arg:
39
31
0
0
8
8
0
0
0
31
16
31
8
0
8
% R
% Ser:
0
24
0
0
0
16
16
47
31
0
24
16
16
8
16
% S
% Thr:
0
8
8
0
8
16
16
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
8
0
8
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _