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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TM9SF2 All Species: 10
Human Site: S20 Identified Species: 20
UniProt: Q99805 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99805 NP_004791.1 663 75776 S20 W P R L L L L S L L L L G A V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534172 662 75623 L20 W P G L V L L L L L L R A A P
Cat Felis silvestris
Mouse Mus musculus P58021 662 75312 S20 G S R L L L L S L L L L G T V
Rat Rattus norvegicus Q66HG5 663 75568 S20 G P R L L L L S L L L L G T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506557 617 70846 S12 D E E A F L R S G I E L F V N
Chicken Gallus gallus XP_416972 651 74239 A22 T A P P P P A A G F Y L P G L
Frog Xenopus laevis NP_001088583 651 74212 A22 L C V I R P G A A F Y L P G L
Zebra Danio Brachydanio rerio NP_997893 658 75037 L20 S L F L C G L L Q D A L S F Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610053 659 74623 T20 V V L L H L A T P T Q A F Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_509429 655 75309 A20 L V S F L A S A S A F Y L P G
Sea Urchin Strong. purpuratus XP_793969 666 76548 V20 C F I L A T H V E A F Y L P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32802 667 75944 K21 Y F F V S T V K A F Y L P G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.2 N.A. 95.6 95.7 N.A. 88 90.5 86.1 83.5 N.A. 67.4 N.A. 61.8 68.9
Protein Similarity: 100 N.A. N.A. 98.4 N.A. 97.4 97.5 N.A. 90.6 93.8 91.4 89.8 N.A. 80.3 N.A. 76.9 80.6
P-Site Identity: 100 N.A. N.A. 60 N.A. 80 86.6 N.A. 20 6.6 6.6 20 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 66.6 N.A. 80 86.6 N.A. 26.6 20 26.6 20 N.A. 26.6 N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 9 9 17 25 17 17 9 9 9 17 0 % A
% Cys: 9 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 9 9 0 0 0 0 0 9 0 9 0 0 0 0 % E
% Phe: 0 17 17 9 9 0 0 0 0 25 17 0 17 9 0 % F
% Gly: 17 0 9 0 0 9 9 0 17 0 0 0 25 25 17 % G
% His: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 17 9 9 59 34 50 42 17 34 34 34 67 17 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 25 9 9 9 17 0 0 9 0 0 0 25 17 9 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % Q
% Arg: 0 0 25 0 9 0 9 0 0 0 0 9 0 0 0 % R
% Ser: 9 9 9 0 9 0 9 34 9 0 0 0 9 0 0 % S
% Thr: 9 0 0 0 0 17 0 9 0 9 0 0 0 17 0 % T
% Val: 9 17 9 9 9 0 9 9 0 0 0 0 0 9 34 % V
% Trp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 25 17 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _