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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF2
All Species:
9.39
Human Site:
Y217
Identified Species:
18.79
UniProt:
Q99805
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99805
NP_004791.1
663
75776
Y217
N
H
V
D
I
K
I
Y
Y
H
V
V
E
T
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534172
662
75623
Y216
N
H
V
D
I
K
I
Y
Y
H
V
V
E
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P58021
662
75312
Y216
N
H
V
D
I
K
I
Y
Y
H
V
V
E
T
G
Rat
Rattus norvegicus
Q66HG5
663
75568
Q217
N
H
V
D
I
K
I
Q
Y
H
V
V
E
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506557
617
70846
C204
T
H
L
E
K
P
D
C
S
G
L
P
M
D
I
Chicken
Gallus gallus
XP_416972
651
74239
R217
E
N
E
A
L
G
A
R
L
V
A
A
K
L
E
Frog
Xenopus laevis
NP_001088583
651
74212
R217
E
N
E
G
Q
G
A
R
L
V
A
A
K
L
E
Zebra Danio
Brachydanio rerio
NP_997893
658
75037
F212
N
H
V
D
I
T
I
F
Y
H
N
V
E
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610053
659
74623
G213
S
G
Q
S
E
D
W
G
I
Q
F
G
N
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509429
655
75309
N212
R
D
M
T
N
D
G
N
F
L
E
H
K
V
G
Sea Urchin
Strong. purpuratus
XP_793969
666
76548
S218
N
I
T
I
A
F
H
S
L
D
D
G
I
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
H221
E
L
P
Y
F
A
N
H
F
D
I
M
I
E
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.2
N.A.
95.6
95.7
N.A.
88
90.5
86.1
83.5
N.A.
67.4
N.A.
61.8
68.9
Protein Similarity:
100
N.A.
N.A.
98.4
N.A.
97.4
97.5
N.A.
90.6
93.8
91.4
89.8
N.A.
80.3
N.A.
76.9
80.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
93.3
N.A.
6.6
0
0
66.6
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
93.3
N.A.
26.6
20
13.3
73.3
N.A.
20
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
17
0
0
0
17
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
42
0
17
9
0
0
17
9
0
0
9
0
% D
% Glu:
25
0
17
9
9
0
0
0
0
0
9
0
42
9
25
% E
% Phe:
0
0
0
0
9
9
0
9
17
0
9
0
0
0
0
% F
% Gly:
0
9
0
9
0
17
9
9
0
9
0
17
0
0
50
% G
% His:
0
50
0
0
0
0
9
9
0
42
0
9
0
0
0
% H
% Ile:
0
9
0
9
42
0
42
0
9
0
9
0
17
0
9
% I
% Lys:
0
0
0
0
9
34
0
0
0
0
0
0
25
0
0
% K
% Leu:
0
9
9
0
9
0
0
0
25
9
9
0
0
17
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% M
% Asn:
50
17
0
0
9
0
9
9
0
0
9
0
9
17
0
% N
% Pro:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
9
0
9
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
17
0
0
0
0
0
0
9
% R
% Ser:
9
0
0
9
0
0
0
9
9
0
0
0
0
9
0
% S
% Thr:
9
0
9
9
0
9
0
0
0
0
0
0
0
34
0
% T
% Val:
0
0
42
0
0
0
0
0
0
17
34
42
0
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
25
42
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _