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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF2
All Species:
25.45
Human Site:
Y269
Identified Species:
50.91
UniProt:
Q99805
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99805
NP_004791.1
663
75776
Y269
S
G
E
I
K
I
A
Y
T
Y
S
V
S
F
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534172
662
75623
Y268
S
G
E
I
K
I
A
Y
T
Y
S
V
S
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
P58021
662
75312
Y268
S
G
E
I
K
I
A
Y
T
Y
S
I
S
F
E
Rat
Rattus norvegicus
Q66HG5
663
75568
Y269
S
G
E
I
K
I
A
Y
T
Y
S
I
S
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506557
617
70846
F256
P
H
T
H
I
Q
W
F
S
I
M
N
S
L
V
Chicken
Gallus gallus
XP_416972
651
74239
I269
S
F
Q
E
E
K
N
I
R
W
A
S
R
W
D
Frog
Xenopus laevis
NP_001088583
651
74212
I269
S
F
H
E
E
K
N
I
R
W
A
S
R
W
D
Zebra Danio
Brachydanio rerio
NP_997893
658
75037
Y264
N
G
E
I
R
I
P
Y
T
Y
S
V
K
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610053
659
74623
Y265
G
E
Q
L
E
I
V
Y
T
Y
S
V
K
F
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509429
655
75309
Y264
S
A
E
I
T
Y
S
Y
S
I
K
W
T
K
T
Sea Urchin
Strong. purpuratus
XP_793969
666
76548
Y270
N
K
D
L
D
I
T
Y
S
Y
S
V
H
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
V273
D
E
G
N
D
N
E
V
Y
F
T
Y
S
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.2
N.A.
95.6
95.7
N.A.
88
90.5
86.1
83.5
N.A.
67.4
N.A.
61.8
68.9
Protein Similarity:
100
N.A.
N.A.
98.4
N.A.
97.4
97.5
N.A.
90.6
93.8
91.4
89.8
N.A.
80.3
N.A.
76.9
80.6
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
6.6
66.6
N.A.
46.6
N.A.
26.6
40
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
46.6
40
80
N.A.
66.6
N.A.
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
34
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
17
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
17
50
17
25
0
9
0
0
0
0
0
0
0
25
% E
% Phe:
0
17
0
0
0
0
0
9
0
9
0
0
0
59
0
% F
% Gly:
9
42
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
9
9
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
50
9
59
0
17
0
17
0
17
0
0
9
% I
% Lys:
0
9
0
0
34
17
0
0
0
0
9
0
17
9
9
% K
% Leu:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
17
0
0
9
0
9
17
0
0
0
0
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
9
0
0
0
17
0
0
0
17
0
0
% R
% Ser:
59
0
0
0
0
0
9
0
25
0
59
17
50
0
0
% S
% Thr:
0
0
9
0
9
0
9
0
50
0
9
0
9
0
9
% T
% Val:
0
0
0
0
0
0
9
9
0
0
0
42
0
9
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
17
0
9
0
17
0
% W
% Tyr:
0
0
0
0
0
9
0
67
9
59
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _