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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF2
All Species:
43.03
Human Site:
Y517
Identified Species:
86.06
UniProt:
Q99805
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99805
NP_004791.1
663
75776
Y517
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534172
662
75623
Y516
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Cat
Felis silvestris
Mouse
Mus musculus
P58021
662
75312
Y516
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Rat
Rattus norvegicus
Q66HG5
663
75568
Y517
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506557
617
70846
L484
G
I
I
M
G
G
I
L
P
F
G
C
I
F
I
Chicken
Gallus gallus
XP_416972
651
74239
Y505
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Frog
Xenopus laevis
NP_001088583
651
74212
Y505
Q
I
P
D
Q
S
F
Y
T
K
P
L
P
G
I
Zebra Danio
Brachydanio rerio
NP_997893
658
75037
Y512
Q
I
P
E
Q
S
F
Y
T
K
P
L
P
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610053
659
74623
Y513
Q
I
P
D
Q
S
I
Y
T
Q
P
I
P
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509429
655
75309
Y509
Q
V
P
E
Q
T
F
Y
T
K
P
L
P
G
M
Sea Urchin
Strong. purpuratus
XP_793969
666
76548
Y520
Q
I
P
E
Q
S
F
Y
T
R
P
F
P
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
Y522
Q
I
P
F
Q
P
W
Y
L
K
T
I
P
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.2
N.A.
95.6
95.7
N.A.
88
90.5
86.1
83.5
N.A.
67.4
N.A.
61.8
68.9
Protein Similarity:
100
N.A.
N.A.
98.4
N.A.
97.4
97.5
N.A.
90.6
93.8
91.4
89.8
N.A.
80.3
N.A.
76.9
80.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
100
93.3
100
N.A.
73.3
N.A.
80
86.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
93.3
N.A.
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
75
0
0
9
0
9
0
9
0
% F
% Gly:
9
0
0
0
9
9
0
0
0
0
9
0
0
84
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
92
9
0
0
0
17
0
0
0
0
17
9
0
84
% I
% Lys:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
9
0
0
67
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
92
0
0
9
0
0
9
0
84
0
92
0
0
% P
% Gln:
92
0
0
0
92
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
84
0
9
0
0
0
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _