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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRRX2 All Species: 11.52
Human Site: S171 Identified Species: 28.15
UniProt: Q99811 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99811 NP_057391.1 253 27079 S171 R A M L A S R S A S L L K S Y
Chimpanzee Pan troglodytes A2T711 184 20085 A103 A A P R L P E A P A L P F A R
Rhesus Macaque Macaca mulatta XP_001097278 198 22227 L117 L A N K N A S L L K S Y S G D
Dog Lupus familis XP_548419 212 23753 S130 R A M L A N R S A T L L K S Y
Cat Felis silvestris
Mouse Mus musculus Q06348 247 26408 S165 R A M L A T R S A S L L K S Y
Rat Rattus norvegicus P63014 245 27251 S163 M L A N K N A S L L K S Y S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514860 202 23193 L121 L A N K N A S L L K S Y S G E
Chicken Gallus gallus Q05437 245 27183 S163 M L A S K N A S L L K S Y S G
Frog Xenopus laevis O42567 325 36295 N207 D S P M L S F N R S P Q P S A
Zebra Danio Brachydanio rerio O42356 330 36917 S247 S S A T P V H S I P G F M G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.5 53.3 71.1 N.A. 89.3 60 N.A. 51.3 59.6 30.7 27.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 29.2 63.2 73.5 N.A. 91.3 71.5 N.A. 62 71.5 43 40.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 86.6 N.A. 93.3 13.3 N.A. 6.6 13.3 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 13.3 100 N.A. 100 20 N.A. 13.3 20 40 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 60 30 0 30 20 20 10 30 10 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 30 20 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 20 20 0 0 0 0 20 20 0 30 0 0 % K
% Leu: 20 20 0 30 20 0 0 20 40 20 40 30 0 0 0 % L
% Met: 20 0 30 10 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 20 10 20 30 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 0 10 10 0 0 10 10 10 10 10 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 30 0 0 10 0 0 30 0 10 0 0 0 0 0 10 % R
% Ser: 10 20 0 10 0 20 20 60 0 30 20 20 20 60 0 % S
% Thr: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 20 20 0 30 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _