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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRRX2 All Species: 0.3
Human Site: S80 Identified Species: 0.74
UniProt: Q99811 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99811 NP_057391.1 253 27079 S80 P S G G S S G S E A A P Q D G
Chimpanzee Pan troglodytes A2T711 184 20085 P23 L G P G E E A P K K K H R R N
Rhesus Macaque Macaca mulatta XP_001097278 198 22227 L37 P Q Q D N D Q L N S E E K K K
Dog Lupus familis XP_548419 212 23753 Q42 P T L A P E R Q P H S G E C P
Cat Felis silvestris
Mouse Mus musculus Q06348 247 26408 S74 R E P S G G S S G T E A A P Q
Rat Rattus norvegicus P63014 245 27251 L70 S L L E S P G L T S G S D T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514860 202 23193 L41 N A D V D D Q L N S E E K K K
Chicken Gallus gallus Q05437 245 27183 L70 S L L E S P G L T S G S D T P
Frog Xenopus laevis O42567 325 36295 L106 A K T S S E C L S P G L S T S
Zebra Danio Brachydanio rerio O42356 330 36917 D113 K C D G D L G D L R K A I E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.5 53.3 71.1 N.A. 89.3 60 N.A. 51.3 59.6 30.7 27.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 29.2 63.2 73.5 N.A. 91.3 71.5 N.A. 62 71.5 43 40.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 13.3 N.A. 0 13.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 26.6 26.6 N.A. 6.6 20 N.A. 20 20 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 0 10 0 0 10 10 20 10 0 0 % A
% Cys: 0 10 0 0 0 0 10 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 20 10 20 20 0 10 0 0 0 0 20 10 0 % D
% Glu: 0 10 0 20 10 30 0 0 10 0 30 20 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 30 10 10 40 0 10 0 30 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 10 10 0 0 0 0 0 0 10 10 20 0 20 20 20 % K
% Leu: 10 20 30 0 0 10 0 50 10 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 0 20 0 0 0 0 0 10 % N
% Pro: 30 0 20 0 10 20 0 10 10 10 0 10 0 10 30 % P
% Gln: 0 10 10 0 0 0 20 10 0 0 0 0 10 0 10 % Q
% Arg: 10 0 0 0 0 0 10 0 0 10 0 0 10 10 0 % R
% Ser: 20 10 0 20 40 10 10 20 10 40 10 20 10 0 20 % S
% Thr: 0 10 10 0 0 0 0 0 20 10 0 0 0 30 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _