KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRRX2
All Species:
1.21
Human Site:
S91
Identified Species:
2.96
UniProt:
Q99811
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99811
NP_057391.1
253
27079
S91
P
Q
D
G
E
C
P
S
P
G
R
G
S
A
A
Chimpanzee
Pan troglodytes
A2T711
184
20085
F34
H
R
R
N
R
T
T
F
T
T
Y
Q
L
H
Q
Rhesus Macaque
Macaca mulatta
XP_001097278
198
22227
R48
E
K
K
K
R
K
Q
R
R
N
R
T
T
F
N
Dog
Lupus familis
XP_548419
212
23753
R53
G
E
C
P
S
P
G
R
G
G
A
A
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q06348
247
26408
C85
A
A
P
Q
D
G
D
C
P
S
P
G
R
G
T
Rat
Rattus norvegicus
P63014
245
27251
N81
S
D
T
P
Q
Q
D
N
D
Q
L
N
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514860
202
23193
R52
E
K
K
K
R
K
Q
R
R
N
R
T
T
F
N
Chicken
Gallus gallus
Q05437
245
27183
N81
S
D
T
P
Q
Q
D
N
D
Q
L
N
S
E
E
Frog
Xenopus laevis
O42567
325
36295
N117
L
S
T
S
N
S
D
N
K
L
S
D
D
E
Q
Zebra Danio
Brachydanio rerio
O42356
330
36917
S124
A
I
E
S
D
S
K
S
P
D
S
A
D
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
53.3
71.1
N.A.
89.3
60
N.A.
51.3
59.6
30.7
27.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
29.2
63.2
73.5
N.A.
91.3
71.5
N.A.
62
71.5
43
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
6.6
N.A.
13.3
6.6
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
13.3
N.A.
20
20
N.A.
20
20
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
0
0
0
0
0
0
0
10
20
0
10
10
% A
% Cys:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
20
10
0
20
0
40
0
20
10
0
10
20
0
0
% D
% Glu:
20
10
10
0
10
0
0
0
0
0
0
0
0
30
30
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% F
% Gly:
10
0
0
10
0
10
10
0
10
20
0
20
0
20
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
20
20
0
20
10
0
10
0
0
0
10
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
10
20
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
30
0
20
0
20
0
0
20
% N
% Pro:
10
0
10
30
0
10
10
0
30
0
10
0
0
0
0
% P
% Gln:
0
10
0
10
20
20
20
0
0
20
0
10
0
0
20
% Q
% Arg:
0
10
10
0
30
0
0
30
20
0
30
0
10
10
0
% R
% Ser:
20
10
0
20
10
20
0
20
0
10
20
0
30
0
0
% S
% Thr:
0
0
30
0
0
10
10
0
10
10
0
20
20
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _