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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSG101 All Species: 18.18
Human Site: S162 Identified Species: 30.77
UniProt: Q99816 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99816 NP_006283.1 390 43944 S162 A T G P P N T S Y M P G M P G
Chimpanzee Pan troglodytes XP_508319 403 45626 S162 A T G P P N T S Y M P G M P G
Rhesus Macaque Macaca mulatta XP_001083004 378 43027 G157 S Y M P G M P G G I S P Y P S
Dog Lupus familis XP_542525 391 44074 S163 A T G P P N T S Y M P S M P S
Cat Felis silvestris
Mouse Mus musculus Q61187 391 44105 S163 A T G P P N T S Y M P G M P S
Rat Rattus norvegicus Q6IRE4 391 44059 S163 A A G P P N T S Y L P S M P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516719 326 36535 P127 Y P A Y P Y P P G P Q Y P A T
Chicken Gallus gallus
Frog Xenopus laevis NP_001084620 394 44396 P166 P P N S S Y M P G V M P P Y P
Zebra Danio Brachydanio rerio Q6DBY5 471 51246 S178 P D Q E V K V S V I G G G D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524120 408 45172 G183 P T A G G A G G S N F P P Y P
Honey Bee Apis mellifera XP_392951 416 46489 N191 S Q Y T G G N N I Y P P Y M S
Nematode Worm Caenorhab. elegans NP_500364 425 46214 S200 P S S T P Y P S A G A M G Y N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LHG8 398 44697 V174 P P P S P P T V Y D S S L S R
Baker's Yeast Sacchar. cerevisiae P25604 385 43312 P167 A P S L P P K P N T Q L Q Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 91.5 97.6 N.A. 94.6 93.6 N.A. 62.3 N.A. 82.2 24.6 N.A. 50.7 49 39.5 N.A.
Protein Similarity: 100 92.8 92.5 98.2 N.A. 97.4 96.6 N.A. 68.2 N.A. 90.3 42.8 N.A. 67.8 66.1 58.5 N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 73.3 N.A. 6.6 N.A. 0 13.3 N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 100 26.6 86.6 N.A. 93.3 80 N.A. 6.6 N.A. 6.6 20 N.A. 6.6 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 46.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 15 0 0 8 0 0 8 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 36 8 22 8 8 15 22 8 8 29 15 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 15 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 0 0 0 8 0 8 8 0 8 % L
% Met: 0 0 8 0 0 8 8 0 0 29 8 8 36 8 0 % M
% Asn: 0 0 8 0 0 36 8 8 8 8 0 0 0 0 8 % N
% Pro: 36 29 8 43 65 15 22 22 0 8 43 29 22 43 15 % P
% Gln: 0 8 8 0 0 0 0 0 0 0 15 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 15 8 15 15 8 0 0 50 8 0 15 22 0 8 36 % S
% Thr: 0 36 0 15 0 0 43 0 0 8 0 0 0 0 8 % T
% Val: 0 0 0 0 8 0 8 8 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 8 8 0 22 0 0 43 8 0 8 15 22 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _