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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSG101
All Species:
26.06
Human Site:
S222
Identified Species:
44.1
UniProt:
Q99816
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99816
NP_006283.1
390
43944
S222
P
S
R
D
G
T
I
S
E
D
T
I
R
A
S
Chimpanzee
Pan troglodytes
XP_508319
403
45626
S222
P
S
R
D
G
T
I
S
E
D
T
I
R
A
S
Rhesus Macaque
Macaca mulatta
XP_001083004
378
43027
S217
S
E
D
T
I
R
A
S
L
I
S
A
V
S
D
Dog
Lupus familis
XP_542525
391
44074
S223
P
S
R
D
G
T
I
S
E
D
T
I
R
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61187
391
44105
S223
P
S
R
D
G
T
I
S
E
D
T
I
R
A
S
Rat
Rattus norvegicus
Q6IRE4
391
44059
S223
P
S
R
D
G
T
I
S
E
D
T
I
R
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516719
326
36535
A187
E
E
M
D
R
A
Q
A
E
L
N
A
L
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084620
394
44396
G226
P
A
R
D
G
T
I
G
E
D
T
I
R
A
S
Zebra Danio
Brachydanio rerio
Q6DBY5
471
51246
G238
K
D
L
S
A
S
A
G
S
K
V
L
V
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524120
408
45172
T243
P
S
S
T
G
T
I
T
E
E
H
I
K
A
S
Honey Bee
Apis mellifera
XP_392951
416
46489
T251
V
S
A
S
G
T
I
T
E
E
H
I
R
A
S
Nematode Worm
Caenorhab. elegans
NP_500364
425
46214
Q260
S
S
S
G
G
T
I
Q
A
D
T
I
R
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LHG8
398
44697
M234
A
I
N
K
M
V
E
M
V
H
S
D
L
V
S
Baker's Yeast
Sacchar. cerevisiae
P25604
385
43312
N227
N
H
H
E
M
L
Q
N
L
Q
T
V
V
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91.5
97.6
N.A.
94.6
93.6
N.A.
62.3
N.A.
82.2
24.6
N.A.
50.7
49
39.5
N.A.
Protein Similarity:
100
92.8
92.5
98.2
N.A.
97.4
96.6
N.A.
68.2
N.A.
90.3
42.8
N.A.
67.8
66.1
58.5
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
13.3
N.A.
86.6
0
N.A.
60
60
66.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
20
N.A.
93.3
20
N.A.
80
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
46.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
8
8
15
8
8
0
0
15
0
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
50
0
0
0
0
0
50
0
8
0
0
8
% D
% Glu:
8
15
0
8
0
0
8
0
65
15
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
65
0
0
15
0
0
0
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
8
15
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
65
0
0
8
0
65
0
8
0
% I
% Lys:
8
0
0
8
0
0
0
0
0
8
0
0
8
8
0
% K
% Leu:
0
0
8
0
0
8
0
0
15
8
0
8
15
0
0
% L
% Met:
0
0
8
0
15
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
8
0
0
8
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
15
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
43
0
8
8
0
0
0
0
0
0
58
0
8
% R
% Ser:
15
58
15
15
0
8
0
43
8
0
15
0
0
8
72
% S
% Thr:
0
0
0
15
0
65
0
15
0
0
58
0
0
0
8
% T
% Val:
8
0
0
0
0
8
0
0
8
0
8
8
22
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _