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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSG101 All Species: 39.39
Human Site: S367 Identified Species: 66.67
UniProt: Q99816 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99816 NP_006283.1 390 43944 S367 L K H V R L L S R K Q F Q L R
Chimpanzee Pan troglodytes XP_508319 403 45626 T367 L K V F L H F T F Q D F L T W
Rhesus Macaque Macaca mulatta XP_001083004 378 43027 S355 L K H V R L L S R K Q F Q L R
Dog Lupus familis XP_542525 391 44074 S368 L K H V R L L S R K Q F Q L R
Cat Felis silvestris
Mouse Mus musculus Q61187 391 44105 S368 L K H V R L L S R K Q F Q L R
Rat Rattus norvegicus Q6IRE4 391 44059 S368 L K H V R L L S R K Q F Q L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516719 326 36535 K305 H V R L L S R K Q F Q L R A L
Chicken Gallus gallus
Frog Xenopus laevis NP_001084620 394 44396 S371 L K H V R L L S R K Q F Q L R
Zebra Danio Brachydanio rerio Q6DBY5 471 51246 G385 F E M I K G R G Q R S W S V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524120 408 45172 S387 L K H V R Q L S R K Q F I L R
Honey Bee Apis mellifera XP_392951 416 46489 S395 L K Q V R Q L S R R Q F M L R
Nematode Worm Caenorhab. elegans NP_500364 425 46214 S404 L R H V R D V S R E Q F I Y R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LHG8 398 44697 S367 L R N V R L L S R E Q F F H R
Baker's Yeast Sacchar. cerevisiae P25604 385 43312 G363 L D T F V K Q G R E L A R Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 91.5 97.6 N.A. 94.6 93.6 N.A. 62.3 N.A. 82.2 24.6 N.A. 50.7 49 39.5 N.A.
Protein Similarity: 100 92.8 92.5 98.2 N.A. 97.4 96.6 N.A. 68.2 N.A. 90.3 42.8 N.A. 67.8 66.1 58.5 N.A.
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. 6.6 N.A. 100 0 N.A. 86.6 73.3 60 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 26.6 N.A. 100 46.6 N.A. 86.6 80 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 46.9 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 22 0 0 0 0 0 % E
% Phe: 8 0 0 15 0 0 8 0 8 8 0 79 8 0 0 % F
% Gly: 0 0 0 0 0 8 0 15 0 0 0 0 0 0 8 % G
% His: 8 0 58 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 65 0 0 8 8 0 8 0 50 0 0 0 0 0 % K
% Leu: 86 0 0 8 15 50 65 0 0 0 8 8 8 58 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 15 8 0 15 8 79 0 43 8 8 % Q
% Arg: 0 15 8 0 72 0 15 0 79 15 0 0 15 0 72 % R
% Ser: 0 0 0 0 0 8 0 72 0 0 8 0 8 0 0 % S
% Thr: 0 0 8 0 0 0 0 8 0 0 0 0 0 8 0 % T
% Val: 0 8 8 72 8 0 8 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _