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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSG101
All Species:
37.58
Human Site:
S48
Identified Species:
63.59
UniProt:
Q99816
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99816
NP_006283.1
390
43944
S48
S
Y
V
F
N
D
G
S
S
R
E
L
M
N
L
Chimpanzee
Pan troglodytes
XP_508319
403
45626
S48
S
Y
V
F
N
D
G
S
S
R
E
L
M
N
L
Rhesus Macaque
Macaca mulatta
XP_001083004
378
43027
S48
S
Y
V
F
N
D
G
S
S
R
E
L
M
N
L
Dog
Lupus familis
XP_542525
391
44074
S48
S
Y
V
F
N
D
G
S
S
R
E
L
M
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61187
391
44105
S48
S
Y
V
F
N
D
G
S
S
R
E
L
V
N
L
Rat
Rattus norvegicus
Q6IRE4
391
44059
S48
S
Y
V
F
N
D
G
S
S
R
E
L
V
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516719
326
36535
P19
R
S
S
Q
R
F
P
P
G
S
S
S
G
C
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084620
394
44396
S48
S
Y
V
F
N
D
G
S
S
R
E
L
L
S
L
Zebra Danio
Brachydanio rerio
Q6DBY5
471
51246
L48
T
Y
T
S
S
D
S
L
Q
K
D
L
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524120
408
45172
S49
R
F
V
F
N
D
G
S
S
K
E
L
F
T
I
Honey Bee
Apis mellifera
XP_392951
416
46489
S49
P
F
V
F
N
D
G
S
R
K
E
L
F
N
L
Nematode Worm
Caenorhab. elegans
NP_500364
425
46214
K48
T
F
M
F
P
D
G
K
R
R
T
A
F
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LHG8
398
44697
R64
S
F
M
H
N
D
G
R
S
V
N
L
L
Q
A
Baker's Yeast
Sacchar. cerevisiae
P25604
385
43312
T58
V
F
T
H
S
D
G
T
P
Q
L
L
L
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91.5
97.6
N.A.
94.6
93.6
N.A.
62.3
N.A.
82.2
24.6
N.A.
50.7
49
39.5
N.A.
Protein Similarity:
100
92.8
92.5
98.2
N.A.
97.4
96.6
N.A.
68.2
N.A.
90.3
42.8
N.A.
67.8
66.1
58.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
86.6
26.6
N.A.
60
66.6
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
100
60
N.A.
80
80
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
46.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
93
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% E
% Phe:
0
36
0
72
0
8
0
0
0
0
0
0
22
0
0
% F
% Gly:
0
0
0
0
0
0
86
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
0
0
0
0
0
0
8
0
22
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
86
29
0
72
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
29
0
0
% M
% Asn:
0
0
0
0
72
0
0
0
0
0
8
0
0
50
0
% N
% Pro:
8
0
0
0
8
0
8
8
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
8
8
0
0
0
8
0
% Q
% Arg:
15
0
0
0
8
0
0
8
15
58
0
0
0
8
0
% R
% Ser:
58
8
8
8
15
0
8
65
65
8
8
8
0
15
0
% S
% Thr:
15
0
15
0
0
0
0
8
0
0
8
0
0
8
0
% T
% Val:
8
0
65
0
0
0
0
0
0
8
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _