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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSG101
All Species:
20.91
Human Site:
Y178
Identified Species:
35.38
UniProt:
Q99816
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99816
NP_006283.1
390
43944
Y178
I
S
P
Y
P
S
G
Y
P
P
N
P
S
G
Y
Chimpanzee
Pan troglodytes
XP_508319
403
45626
Y178
I
S
P
Y
P
S
G
Y
P
P
N
P
S
G
Y
Rhesus Macaque
Macaca mulatta
XP_001083004
378
43027
Y173
Y
P
P
N
P
S
G
Y
P
G
C
P
Y
P
P
Dog
Lupus familis
XP_542525
391
44074
Y179
I
S
A
Y
P
S
G
Y
P
P
N
P
S
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61187
391
44105
Y179
I
S
A
Y
P
S
G
Y
P
P
N
P
S
G
Y
Rat
Rattus norvegicus
Q6IRE4
391
44059
Y179
I
S
A
Y
P
S
G
Y
P
P
N
P
S
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516719
326
36535
Q143
S
S
Q
H
Y
P
A
Q
P
P
G
T
T
V
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084620
394
44396
S182
T
A
H
P
A
N
P
S
G
Y
T
G
F
P
Y
Zebra Danio
Brachydanio rerio
Q6DBY5
471
51246
M194
I
A
A
V
L
S
I
M
A
K
S
C
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524120
408
45172
P199
G
S
N
V
G
P
Y
P
P
T
P
A
G
P
A
Honey Bee
Apis mellifera
XP_392951
416
46489
Q207
T
S
S
G
F
P
Y
Q
G
Y
G
S
Y
G
G
Nematode Worm
Caenorhab. elegans
NP_500364
425
46214
T216
Y
M
N
V
P
Q
S
T
P
Y
P
M
G
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LHG8
398
44697
P190
P
S
A
D
Q
S
L
P
R
P
F
P
P
S
P
Baker's Yeast
Sacchar. cerevisiae
P25604
385
43312
K183
N
T
P
P
L
P
P
K
P
K
S
P
H
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91.5
97.6
N.A.
94.6
93.6
N.A.
62.3
N.A.
82.2
24.6
N.A.
50.7
49
39.5
N.A.
Protein Similarity:
100
92.8
92.5
98.2
N.A.
97.4
96.6
N.A.
68.2
N.A.
90.3
42.8
N.A.
67.8
66.1
58.5
N.A.
P-Site Identity:
100
100
46.6
93.3
N.A.
93.3
93.3
N.A.
20
N.A.
6.6
13.3
N.A.
13.3
13.3
13.3
N.A.
P-Site Similarity:
100
100
46.6
93.3
N.A.
93.3
93.3
N.A.
33.3
N.A.
20
26.6
N.A.
13.3
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
46.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
36
0
8
0
8
0
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
8
0
0
8
8
0
43
0
15
8
15
8
15
43
15
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
43
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
15
0
0
0
0
15
% K
% Leu:
0
0
0
0
15
0
8
0
0
0
0
0
0
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
15
8
0
8
0
0
0
0
36
0
0
0
0
% N
% Pro:
8
8
29
15
50
29
15
15
72
50
15
58
8
22
15
% P
% Gln:
0
0
8
0
8
8
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
65
8
0
0
58
8
8
0
0
15
8
36
8
8
% S
% Thr:
15
8
0
0
0
0
0
8
0
8
8
8
8
0
0
% T
% Val:
0
0
0
22
0
0
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
36
8
0
15
43
0
22
0
0
15
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _