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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGDIG All Species: 16.97
Human Site: T163 Identified Species: 37.33
UniProt: Q99819 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99819 NP_001167.2 225 25098 T163 R G L R V D K T V Y M V G S Y
Chimpanzee Pan troglodytes XP_001171621 242 27108 T180 R G L R V D K T V Y M V G S Y
Rhesus Macaque Macaca mulatta XP_001118456 217 24079 T155 R G L R V D K T V Y M V G S Y
Dog Lupus familis XP_854314 246 26701 A184 Q G L R V D K A V Y M V G S Y
Cat Felis silvestris
Mouse Mus musculus Q62160 225 25278 A163 R G L R V D K A I F M V G S Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515491 219 25235 A157 K G L R V D K A V Y M V G S Y
Chicken Gallus gallus NP_001074340 204 23256 T142 K G V K I V K T E Y M V G S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20496 191 21900 E132 S G I T V E N E K Y M M G S Y
Sea Urchin Strong. purpuratus XP_781627 200 22679 S139 K G I K V D K S S L M V G S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFC6 240 27213 A177 T G V K V D R A K E M L G T F
Baker's Yeast Sacchar. cerevisiae Q12434 202 23120 I140 A G I A V D K I D D H L G S Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.1 88.8 69.9 N.A. 79.5 N.A. N.A. 60.4 52.8 N.A. N.A. N.A. N.A. N.A. 30.2 41.3
Protein Similarity: 100 87.5 90.6 77.2 N.A. 88.8 N.A. N.A. 72 69.3 N.A. N.A. N.A. N.A. N.A. 45.7 58.2
P-Site Identity: 100 100 100 86.6 N.A. 80 N.A. N.A. 86.6 60 N.A. N.A. N.A. N.A. N.A. 46.6 60
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 93.3 86.6 N.A. N.A. N.A. N.A. N.A. 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 27.5 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. 44.1 49.3 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 37 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 82 0 0 10 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 10 10 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % F
% Gly: 0 100 0 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 28 0 10 0 0 10 10 0 0 0 0 0 0 % I
% Lys: 28 0 0 28 0 0 82 0 19 0 0 0 0 0 0 % K
% Leu: 0 0 55 0 0 0 0 0 0 10 0 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 91 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 37 0 0 55 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 10 10 0 0 0 0 91 0 % S
% Thr: 10 0 0 10 0 0 0 37 0 0 0 0 0 10 0 % T
% Val: 0 0 19 0 91 10 0 0 46 0 0 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 91 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _