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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIG
All Species:
30.61
Human Site:
Y48
Identified Species:
67.33
UniProt:
Q99819
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99819
NP_001167.2
225
25098
Y48
L
D
E
A
V
P
E
Y
R
A
P
G
R
K
S
Chimpanzee
Pan troglodytes
XP_001171621
242
27108
Y65
L
D
E
A
V
P
E
Y
R
A
P
G
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001118456
217
24079
Y40
L
D
E
A
V
P
E
Y
R
A
P
G
R
K
S
Dog
Lupus familis
XP_854314
246
26701
Y69
L
D
E
A
V
P
E
Y
R
A
P
G
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62160
225
25278
Y48
L
D
E
I
V
P
E
Y
Q
A
P
G
K
K
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
Y42
G
D
E
V
E
L
A
Y
Q
A
P
E
K
K
S
Chicken
Gallus gallus
NP_001074340
204
23256
Y27
E
D
E
H
S
V
N
Y
K
P
P
A
R
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
Y16
E
N
T
S
E
Y
Q
Y
K
Q
P
P
Q
K
S
Sea Urchin
Strong. purpuratus
XP_781627
200
22679
Y25
E
P
D
A
T
P
G
Y
Q
P
P
A
K
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
L62
E
E
D
D
D
S
K
L
Q
L
G
P
Q
Y
T
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
Y20
E
E
R
N
N
D
Q
Y
K
V
S
A
K
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
88.8
69.9
N.A.
79.5
N.A.
N.A.
60.4
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
30.2
41.3
Protein Similarity:
100
87.5
90.6
77.2
N.A.
88.8
N.A.
N.A.
72
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
45.7
58.2
P-Site Identity:
100
100
100
100
N.A.
80
N.A.
N.A.
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
49.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
46
0
0
10
0
0
55
0
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
64
19
10
10
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
46
19
64
0
19
0
46
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
10
46
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
28
0
0
0
37
91
0
% K
% Leu:
46
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
55
0
0
0
19
82
19
0
0
0
% P
% Gln:
0
0
0
0
0
0
19
0
37
10
0
0
19
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
37
0
0
0
46
0
0
% R
% Ser:
0
0
0
10
10
10
0
0
0
0
10
0
0
0
73
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
28
% T
% Val:
0
0
0
10
46
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
91
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _