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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT7 All Species: 41.21
Human Site: Y419 Identified Species: 75.56
UniProt: Q99832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99832 NP_001009570.1 543 59367 Y419 I E M E L S K Y L R D Y S R T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104880 543 59344 Y419 I E M E L S K Y L R D Y S R T
Dog Lupus familis XP_852889 543 59402 Y419 I E M E L S K Y L R D Y S R T
Cat Felis silvestris
Mouse Mus musculus P80313 544 59634 Y419 I E M E L S K Y L R D Y S R T
Rat Rattus norvegicus P28480 556 60341 Y422 V E A A L S I Y L E N Y A T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJK8 553 60330 Y419 I E M E L S K Y L R D Y S R T
Frog Xenopus laevis NP_001087037 542 59185 Y419 I E M E L S K Y L R D Y S R T
Zebra Danio Brachydanio rerio NP_775355 547 59781 Y419 I E M E L S K Y L R D Y S R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649835 544 59368 L418 I E M E L S K L L R D Y S R T
Honey Bee Apis mellifera XP_623090 542 59917 T418 I E M E L S K T L R D Y S R V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782448 565 61987 Y439 I E M E L S K Y L R D H S R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28769 545 59211 Y425 V E S A L S V Y L E H L A T T
Baker's Yeast Sacchar. cerevisiae P42943 550 59717 C423 T E M E V S K C L R D Y S K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.8 97.9 N.A. 95.9 34.7 N.A. N.A. 91.8 90.9 87.7 N.A. 75.1 74 N.A. 77.1
Protein Similarity: 100 N.A. 99.8 99 N.A. 97.4 53.5 N.A. N.A. 94.7 95.2 94.6 N.A. 85.8 85.6 N.A. 86.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 40 N.A. N.A. 100 100 100 N.A. 93.3 86.6 N.A. 93.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 66.6 N.A. N.A. 100 100 100 N.A. 93.3 86.6 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 33.7 62.3 N.A.
Protein Similarity: N.A. N.A. N.A. 53.3 77.4 N.A.
P-Site Identity: N.A. N.A. N.A. 40 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 0 0 0 0 0 0 0 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0 % D
% Glu: 0 100 0 85 0 0 0 0 0 16 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 77 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 85 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 93 0 0 8 100 0 0 8 0 0 0 % L
% Met: 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 85 0 0 0 77 0 % R
% Ser: 0 0 8 0 0 100 0 0 0 0 0 0 85 0 8 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 0 0 0 16 85 % T
% Val: 16 0 0 0 8 0 8 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 85 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _