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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT7 All Species: 41.82
Human Site: Y423 Identified Species: 76.67
UniProt: Q99832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99832 NP_001009570.1 543 59367 Y423 L S K Y L R D Y S R T I P G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104880 543 59344 Y423 L S K Y L R D Y S R T I P G K
Dog Lupus familis XP_852889 543 59402 Y423 L S K Y L R D Y S R T I P G K
Cat Felis silvestris
Mouse Mus musculus P80313 544 59634 Y423 L S K Y L R D Y S R T I P G K
Rat Rattus norvegicus P28480 556 60341 Y426 L S I Y L E N Y A T S M G S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJK8 553 60330 Y423 L S K Y L R D Y S R T I P G K
Frog Xenopus laevis NP_001087037 542 59185 Y423 L S K Y L R D Y S R T I P G K
Zebra Danio Brachydanio rerio NP_775355 547 59781 Y423 L S K Y L R D Y S R T I P G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649835 544 59368 Y422 L S K L L R D Y S R T I A G K
Honey Bee Apis mellifera XP_623090 542 59917 Y422 L S K T L R D Y S R V I A G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782448 565 61987 H443 L S K Y L R D H S R T I A G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28769 545 59211 L429 L S V Y L E H L A T T L G S R
Baker's Yeast Sacchar. cerevisiae P42943 550 59717 Y427 V S K C L R D Y S K T I A G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.8 97.9 N.A. 95.9 34.7 N.A. N.A. 91.8 90.9 87.7 N.A. 75.1 74 N.A. 77.1
Protein Similarity: 100 N.A. 99.8 99 N.A. 97.4 53.5 N.A. N.A. 94.7 95.2 94.6 N.A. 85.8 85.6 N.A. 86.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 33.3 N.A. N.A. 100 100 100 N.A. 86.6 80 N.A. 86.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 66.6 N.A. N.A. 100 100 100 N.A. 86.6 80 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 33.7 62.3 N.A.
Protein Similarity: N.A. N.A. N.A. 53.3 77.4 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 16 0 0 0 31 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 16 85 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 85 0 0 0 % I
% Lys: 0 0 85 0 0 0 0 0 0 8 0 0 0 0 85 % K
% Leu: 93 0 0 8 100 0 0 8 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 85 0 0 0 77 0 0 0 0 16 % R
% Ser: 0 100 0 0 0 0 0 0 85 0 8 0 0 16 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 16 85 0 0 0 0 % T
% Val: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 77 0 0 0 85 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _