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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMO
All Species:
12.42
Human Site:
S751
Identified Species:
22.78
UniProt:
Q99835
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99835
NP_005622.1
787
86397
S751
P
Q
D
P
F
L
P
S
A
P
A
P
V
A
W
Chimpanzee
Pan troglodytes
XP_519371
786
86255
S750
P
Q
D
P
F
L
P
S
A
P
A
P
M
A
W
Rhesus Macaque
Macaca mulatta
XP_001093150
786
86256
S750
P
Q
D
P
F
L
P
S
A
P
A
P
T
A
W
Dog
Lupus familis
XP_539381
720
80168
S684
L
Q
D
P
F
L
P
S
A
P
V
P
T
A
W
Cat
Felis silvestris
Mouse
Mus musculus
P56726
793
87281
G757
H
Q
D
P
F
L
P
G
A
S
A
P
R
V
W
Rat
Rattus norvegicus
P97698
793
87357
G757
H
Q
D
P
F
L
P
G
A
S
A
P
R
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509776
697
77420
V667
P
P
P
P
G
P
G
V
W
T
Q
G
R
R
P
Chicken
Gallus gallus
O42224
794
88236
G738
P
E
D
E
E
N
P
G
P
S
V
G
H
R
Q
Frog
Xenopus laevis
NP_001082084
814
91998
A754
L
T
D
E
S
R
V
A
Y
V
P
V
P
K
H
Zebra Danio
Brachydanio rerio
NP_571102
822
93043
Q765
Q
G
D
L
S
H
F
Q
Q
S
S
W
Q
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91682
1036
116534
A981
G
E
D
E
L
Q
Q
A
M
R
L
L
N
A
A
Honey Bee
Apis mellifera
XP_395373
1059
119629
A979
I
K
E
V
Y
R
K
A
G
I
G
N
L
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781487
550
60898
L520
S
L
S
T
I
P
V
L
P
A
I
Q
Q
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.4
85.3
N.A.
92.8
93
N.A.
81.8
77.4
70.1
67.2
N.A.
31.7
33.4
N.A.
32.4
Protein Similarity:
100
99.3
99.1
87.6
N.A.
94.6
94.8
N.A.
84.6
83.5
78.7
77.1
N.A.
46.3
48.5
N.A.
44.7
P-Site Identity:
100
93.3
93.3
80
N.A.
66.6
66.6
N.A.
13.3
20
6.6
6.6
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
66.6
66.6
N.A.
13.3
26.6
13.3
13.3
N.A.
26.6
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
24
47
8
39
0
0
47
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
8
24
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
47
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
8
0
8
24
8
0
8
16
0
0
0
% G
% His:
16
0
0
0
0
8
0
0
0
0
0
0
8
0
8
% H
% Ile:
8
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
0
0
0
16
16
% K
% Leu:
16
8
0
8
8
47
0
8
0
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% N
% Pro:
39
8
8
54
0
16
54
0
16
31
8
47
8
8
8
% P
% Gln:
8
47
0
0
0
8
8
8
8
0
8
8
16
0
8
% Q
% Arg:
0
0
0
0
0
16
0
0
0
8
0
0
24
16
0
% R
% Ser:
8
0
8
0
16
0
0
31
0
31
8
0
0
0
8
% S
% Thr:
0
8
0
8
0
0
0
0
0
8
0
0
16
0
0
% T
% Val:
0
0
0
8
0
0
16
8
0
8
16
8
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
47
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _