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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBB4Q All Species: 40.3
Human Site: Y310 Identified Species: 80.61
UniProt: Q99867 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99867 NP_064424.3 434 48435 Y310 R D P R H G C Y L T A A A I F
Chimpanzee Pan troglodytes Q8WP14 444 49773 Y310 C D P R H G R Y L T A A A I F
Rhesus Macaque Macaca mulatta XP_001104203 446 50230 Y310 C D P R H G R Y L T A A A I F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9ERD7 450 50400 Y310 C D P R H G R Y L T V A T V F
Rat Rattus norvegicus Q6P9T8 445 49782 Y310 C D P R H G R Y L T V A A V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P32882 445 49935 Y310 C D P R H G R Y L T V A A I F
Frog Xenopus laevis P30883 445 49797 Y310 C D P R H G R Y L T V A A I F
Zebra Danio Brachydanio rerio NP_001032487 445 49698 Y310 C D P R H G R Y L T V A A I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24560 447 50129 Y310 C D P R H G R Y L T V A A I F
Honey Bee Apis mellifera XP_392313 447 50157 Y310 C D P R H G R Y L T V A A I F
Nematode Worm Caenorhab. elegans P41937 444 49782 Y310 C D P R H G R Y L T V A A M F
Sea Urchin Strong. purpuratus XP_791790 447 50098 Y310 C D P R H G R Y L T V A A I F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.3 89.9 N.A. N.A. 81.1 84.7 N.A. N.A. 84 84.9 84.4 N.A. 83.8 83.6 82.8 84.5
Protein Similarity: 100 94.5 93.5 N.A. N.A. 88 91.2 N.A. N.A. 91.2 91.2 91.4 N.A. 90.5 90.5 90.7 91
P-Site Identity: 100 86.6 86.6 N.A. N.A. 66.6 73.3 N.A. N.A. 80 80 80 N.A. 80 80 73.3 80
P-Site Similarity: 100 86.6 86.6 N.A. N.A. 73.3 80 N.A. N.A. 80 80 80 N.A. 80 80 80 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 25 100 92 0 0 % A
% Cys: 92 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 100 0 0 92 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 100 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 75 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _