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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT1
All Species:
43.64
Human Site:
Y270
Identified Species:
80
UniProt:
Q99873
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99873
NP_001527.3
361
41516
Y270
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Chimpanzee
Pan troglodytes
XP_508936
385
44150
Y294
L
Q
I
Q
R
N
D
Y
V
H
A
L
V
T
Y
Rhesus Macaque
Macaca mulatta
XP_001113609
466
52877
Y262
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Dog
Lupus familis
XP_864131
350
40349
Y259
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIF0
371
42417
Y280
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Rat
Rattus norvegicus
Q63009
353
40504
Y262
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521175
437
49423
Y346
L
Q
I
Q
R
N
D
Y
I
H
A
L
V
T
Y
Chicken
Gallus gallus
XP_423669
369
42416
Y278
L
Q
I
Q
R
N
D
Y
I
H
A
L
V
T
Y
Frog
Xenopus laevis
Q8AV13
369
42306
Y278
L
Q
V
K
R
N
D
Y
I
H
A
L
V
A
Y
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
Y328
L
Q
I
Q
R
N
D
Y
V
H
A
L
V
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH48
530
59709
I378
F
H
I
L
Q
T
G
I
C
H
G
L
A
F
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
Y299
L
V
A
Q
R
N
D
Y
I
H
A
L
V
A
Y
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
N252
A
K
R
Q
D
M
I
N
G
I
V
T
W
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
71.2
96.9
N.A.
97
95.2
N.A.
63.8
75
90.7
65.1
N.A.
25
N.A.
N.A.
N.A.
Protein Similarity:
100
84.6
72.9
96.9
N.A.
97.3
96.1
N.A.
75.7
87.5
94.5
77
N.A.
40.7
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
73.3
73.3
93.3
80
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
93.3
100
93.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.8
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.4
65.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
85
0
8
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
85
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
93
0
0
0
0
0
% H
% Ile:
0
0
39
0
0
0
8
8
31
8
0
0
0
0
0
% I
% Lys:
0
8
0
47
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
85
0
0
8
0
0
0
0
0
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
85
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
77
0
47
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
85
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
8
0
31
0
% T
% Val:
0
8
47
0
0
0
0
0
54
0
8
0
85
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
85
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _