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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H2AJ All Species: 34.85
Human Site: T121 Identified Species: 69.7
UniProt: Q99878 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99878 NP_066544.1 128 13936 T121 A V L L P K K T E S H H K T K
Chimpanzee Pan troglodytes XP_001137950 130 14103 T121 A V L L P K K T E S H H K A K
Rhesus Macaque Macaca mulatta XP_001096671 130 14103 T121 A V L L P K K T E S H H K A K
Dog Lupus familis XP_545413 128 13916 T121 A V L L P K K T E S H H K A K
Cat Felis silvestris
Mouse Mus musculus Q8CGP6 128 13932 T121 A V L L P K K T E S H H K A K
Rat Rattus norvegicus P02262 130 14059 T121 A V L L P K K T E S H H K A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513730 130 14089 T121 A V L L P K K T E S H H K A K
Chicken Gallus gallus P02263 129 13922 T121 A V L L P K K T D S H K A K A
Frog Xenopus laevis P06897 130 13948 T121 S V L L P K K T E S A K S A K
Zebra Danio Brachydanio rerio Q7ZUY3 142 14983 T121 A V L L P K K T G Q A A A S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P84051 124 13344
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P16886 126 13432 K119 I Q A V L L P K K T S K A S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 97.6 98.4 N.A. 97.6 96.9 N.A. 96.9 96.1 93 85.2 N.A. 86.7 N.A. N.A. 88.2
Protein Similarity: 100 96.9 98.4 99.2 N.A. 99.2 97.6 N.A. 98.4 97.6 95.3 87.3 N.A. 91.4 N.A. N.A. 92.1
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 66.6 66.6 53.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 73.3 73.3 60 N.A. 0 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 75 0 9 0 0 0 0 0 0 0 17 9 25 59 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 67 59 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 84 84 9 9 0 0 25 59 9 75 % K
% Leu: 0 0 84 84 9 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 84 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 0 0 0 75 9 0 9 17 9 % S
% Thr: 0 0 0 0 0 0 0 84 0 9 0 0 0 9 0 % T
% Val: 0 84 0 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _