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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC6A7 All Species: 21.52
Human Site: T14 Identified Species: 43.03
UniProt: Q99884 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99884 NP_055043.2 636 70893 T14 A H L R K P V T P D L L M T P
Chimpanzee Pan troglodytes XP_527072 813 89904 T191 A H L R K P V T P D L L M T P
Rhesus Macaque Macaca mulatta Q9MYX0 630 70239 L27 D C Q E N G V L Q K V V P T P
Dog Lupus familis XP_546305 590 65600 S9 E T E S R D C S P I T P D L L
Cat Felis silvestris
Mouse Mus musculus Q6PGE7 637 71047 T14 A H L R K P I T P D L L M T P
Rat Rattus norvegicus P28573 637 71072 T14 A H L R K P V T P D L L M T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510332 626 69635 L9 T P V T P D L L M T P S D Q G
Chicken Gallus gallus XP_414596 636 71287 T14 Q Q L R K P V T P E L L V S P
Frog Xenopus laevis A7Y2W8 633 71004 K15 A V P S E A T K K D E N L K R
Zebra Danio Brachydanio rerio NP_001009557 786 87171 N47 A P P P P P V N E R K T F C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VR07 943 103618 S215 S S M R S V V S G Y L P G L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03614 615 69247 T16 P D E K I G R T S N G M Q N A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 42.2 89.7 N.A. 97.8 97.8 N.A. 84.5 86.7 46.3 41.3 N.A. 28.8 N.A. 38.3 N.A.
Protein Similarity: 100 77.9 60.8 91 N.A. 98.4 98.5 N.A. 91 93 66 56.8 N.A. 41.1 N.A. 59.2 N.A.
P-Site Identity: 100 100 20 6.6 N.A. 93.3 100 N.A. 0 66.6 13.3 26.6 N.A. 20 N.A. 6.6 N.A.
P-Site Similarity: 100 100 33.3 20 N.A. 100 100 N.A. 13.3 86.6 26.6 26.6 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 9 0 0 0 0 9 0 0 0 0 0 0 9 0 % C
% Asp: 9 9 0 0 0 17 0 0 0 42 0 0 17 0 0 % D
% Glu: 9 0 17 9 9 0 0 0 9 9 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 17 0 0 9 0 9 0 9 0 9 % G
% His: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 9 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 9 42 0 0 9 9 9 9 0 0 9 0 % K
% Leu: 0 0 42 0 0 0 9 17 0 0 50 42 9 17 9 % L
% Met: 0 0 9 0 0 0 0 0 9 0 0 9 34 0 0 % M
% Asn: 0 0 0 0 9 0 0 9 0 9 0 9 0 9 0 % N
% Pro: 9 17 17 9 17 50 0 0 50 0 9 17 9 0 59 % P
% Gln: 9 9 9 0 0 0 0 0 9 0 0 0 9 9 0 % Q
% Arg: 0 0 0 50 9 0 9 0 0 9 0 0 0 0 9 % R
% Ser: 9 9 0 17 9 0 0 17 9 0 0 9 0 9 9 % S
% Thr: 9 9 0 9 0 0 9 50 0 9 9 9 0 42 0 % T
% Val: 0 9 9 0 0 9 59 0 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _