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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC6A7 All Species: 19.39
Human Site: T20 Identified Species: 38.79
UniProt: Q99884 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99884 NP_055043.2 636 70893 T20 V T P D L L M T P S D Q G D V
Chimpanzee Pan troglodytes XP_527072 813 89904 T197 V T P D L L M T P S D Q G D V
Rhesus Macaque Macaca mulatta Q9MYX0 630 70239 T33 V L Q K V V P T P G D K V E S
Dog Lupus familis XP_546305 590 65600 L15 C S P I T P D L L M T P S D Q
Cat Felis silvestris
Mouse Mus musculus Q6PGE7 637 71047 T20 I T P D L L M T P S D Q G D V
Rat Rattus norvegicus P28573 637 71072 T20 V T P D L L M T P S D Q G D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510332 626 69635 Q15 L L M T P S D Q G D G D L E M
Chicken Gallus gallus XP_414596 636 71287 S20 V T P E L L V S P S S Q D G D
Frog Xenopus laevis A7Y2W8 633 71004 K21 T K K D E N L K R G N W G N Q
Zebra Danio Brachydanio rerio NP_001009557 786 87171 C53 V N E R K T F C P S E N K P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VR07 943 103618 L221 V S G Y L P G L S D S S G N L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03614 615 69247 N22 R T S N G M Q N A T L P I D G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 42.2 89.7 N.A. 97.8 97.8 N.A. 84.5 86.7 46.3 41.3 N.A. 28.8 N.A. 38.3 N.A.
Protein Similarity: 100 77.9 60.8 91 N.A. 98.4 98.5 N.A. 91 93 66 56.8 N.A. 41.1 N.A. 59.2 N.A.
P-Site Identity: 100 100 26.6 13.3 N.A. 93.3 100 N.A. 0 53.3 13.3 20 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 100 53.3 20 N.A. 100 100 N.A. 20 73.3 33.3 26.6 N.A. 40 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 42 0 0 17 0 0 17 42 9 9 50 9 % D
% Glu: 0 0 9 9 9 0 0 0 0 0 9 0 0 17 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 9 0 9 0 9 17 9 0 50 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 9 9 9 9 0 0 9 0 0 0 9 9 0 0 % K
% Leu: 9 17 0 0 50 42 9 17 9 0 9 0 9 0 9 % L
% Met: 0 0 9 0 0 9 34 0 0 9 0 0 0 0 9 % M
% Asn: 0 9 0 9 0 9 0 9 0 0 9 9 0 17 0 % N
% Pro: 0 0 50 0 9 17 9 0 59 0 0 17 0 9 0 % P
% Gln: 0 0 9 0 0 0 9 9 0 0 0 42 0 0 17 % Q
% Arg: 9 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 17 9 0 0 9 0 9 9 50 17 9 9 0 9 % S
% Thr: 9 50 0 9 9 9 0 42 0 9 9 0 0 0 0 % T
% Val: 59 0 0 0 9 9 9 0 0 0 0 0 9 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _