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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A7
All Species:
26.97
Human Site:
T594
Identified Species:
53.94
UniProt:
Q99884
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99884
NP_055043.2
636
70893
T594
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Chimpanzee
Pan troglodytes
XP_527072
813
89904
T771
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
F586
Y
C
I
G
T
S
S
F
V
C
I
P
T
Y
I
Dog
Lupus familis
XP_546305
590
65600
T548
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGE7
637
71047
T594
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Rat
Rattus norvegicus
P28573
637
71072
T594
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510332
626
69635
T584
R
T
G
M
Y
V
A
T
L
A
G
S
Q
S
P
Chicken
Gallus gallus
XP_414596
636
71287
S593
R
T
G
T
Y
V
A
S
L
A
G
S
Q
S
P
Frog
Xenopus laevis
A7Y2W8
633
71004
M592
R
T
G
R
Y
A
Q
M
S
S
T
R
S
E
S
Zebra Danio
Brachydanio rerio
NP_001009557
786
87171
P744
K
L
V
C
S
P
Q
P
D
W
G
P
F
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR07
943
103618
E895
H
C
E
H
D
Y
P
E
Q
E
Q
F
M
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
V574
L
V
G
I
Y
K
F
V
N
A
R
G
N
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
42.2
89.7
N.A.
97.8
97.8
N.A.
84.5
86.7
46.3
41.3
N.A.
28.8
N.A.
38.3
N.A.
Protein Similarity:
100
77.9
60.8
91
N.A.
98.4
98.5
N.A.
91
93
66
56.8
N.A.
41.1
N.A.
59.2
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
86.6
26.6
6.6
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
93.3
33.3
13.3
N.A.
0
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
59
0
0
67
0
0
0
0
9
% A
% Cys:
0
17
0
9
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
9
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
9
9
0
0
% F
% Gly:
0
0
75
9
0
0
0
0
0
0
67
9
0
0
0
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
17
% I
% Lys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
0
0
0
0
59
0
0
0
0
17
0
% L
% Met:
0
0
0
50
0
0
0
9
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
9
9
0
0
0
17
0
0
59
% P
% Gln:
0
0
0
0
0
0
17
0
9
0
9
0
59
0
0
% Q
% Arg:
67
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% R
% Ser:
0
0
0
0
9
9
9
9
9
9
0
59
9
59
9
% S
% Thr:
0
67
0
9
9
0
0
50
0
0
9
0
9
9
0
% T
% Val:
0
9
9
0
0
59
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
9
0
0
0
75
9
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _